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Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma
Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and...
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Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects
It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect...
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Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition
Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence...
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Not every ring scotoma is due to glaucoma
In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...
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Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression
Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...
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Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study
Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...
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Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study
Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...
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Childhood Glaucoma
SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...
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Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony
While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...
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Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains
Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...
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Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom
Purpose: A previously developed machine-learning approach with Kalman filtering technology...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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Clinical classification of childhood glaucomas
Author(s): Yeung HH, Walton DS Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA....
July 31, 2010
Mitochondrial damage in the trabecular meshwork of patients with glaucoma
Author(s): Izzotti A, Saccà SC, Longobardi M, Cartiglia C. Department of Health Sciences, University of Genoa, Genoa, Italy. izzotti@unige.it...
July 31, 2010
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In patients with chronic angle-closure glaucoma and cataract, phacoemulsification with IOL implantation usually results in IOP control up to 2 years after surgery
The Science behind the Tip An anteriorly positioned and thickened lens plays an important role in the pathogenesis of anterior chamber shallowing...
June 30, 2010
Effect of patient's life expectancy on the cost-effectiveness of treatment for ocular hypertension
Author(s): Kymes SM, Plotzke MR, Kass MA, Boland MV, Gordon MO OBJECTIVE: To assess the influence of expected life span on the cost-effectiveness...
June 30, 2010
Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration
Author(s): Baltan S, Inman DM, Danilov CA, Morrison RS, Calkins DJ, Horner PJ. We tested the hypothesis that glaucoma disrupts electrophysiological...
June 30, 2010
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Measurement of central corneal thickness is essential to ensure optimal management of glaucoma patients
The Science behind the Tip The measurement of central corneal thickness (CCT) has emerged as an important parameter to determine in all patients...
May 31, 2010
Delaying Treatment of Ocular Hypertension: the Ocular Hypertension Treatment Study
Author(s): Michael A. Kass, MD; Mae O. Gordon, PhD; Feng Gao, PhD; Dale K. Heuer, MD; Eve J. Higginbotham, MD; Chris A. Johnson, PhD; John K....
May 31, 2010
Neuroprotective Effects of Intravitreal Mesenchymal Stem Cell Transplantation in Experimental Glaucoma
Author(s): Thomas V. Johnson(1,2,3) Natalie D. Bull(1,2) David P. Hunt(1), Nephtali Marina(1), Stanislav I. Tomarev(3), Keith R. Martin(1) Centre...
May 31, 2010
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Disc Haemorrhages
The Science behind the Tip Although described most commonly in normal tension glaucoma, optic disc haemorrhages may occur in all forms of glaucoma....
April 30, 2010
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When should neuroradiological imaging be undertaken in patients with normal tension glaucoma?
The Science behind the Tip Clinicians must remain vigilant to detect intracranial pathology in patients with normal tension glaucoma. Most patients...
March 31, 2010
Simvastatin and Disease Stabilization in Normal Tension Glaucoma: A Cohort Study.
Author(s): Leung DY, Li FC, Kwong YY, Tham CC, Chi SC, Lam DS. Department of Ophthalmology and Visual Sciences, The Chinese University of Hong...
March 31, 2010
Episcleral Venous Pressure Responses to Topical Nitroprusside and N-Nitro-L-arginine Methyl Ester.
Author(s): Zamora DO, Kiel JW. Department of Ophthalmology, University of Texas Health Science Center, San Antonio, Texas. PURPOSE: To determine...
March 31, 2010
Cerebrospinal Fluid Pressure in Glaucoma A Prospective Study.
Author(s): Ren R, Jonas JB, Tian G, Zhen Y, Ma K, Li S, Wang H, Li B, Zhang X, Wang N Beijing Institute of Ophthalmology, Beijing Tongren Eye...
February 28, 2010
Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation.
Author(s): Tezel G, Yang X, Luo C, Cai J, Kain AD, Powell DW, Kuehn MH, Pierce WM Department of Ophthalmology and Visual Sciences, University of...
February 28, 2010
Prediction of glaucomatous visual field loss by extrapolation of linear trends
Author(s): Bengtsson B, Patella VM, Heijl A Departments of Clinical Sciences and Ophthalmology, Lund University, Malmö University Hospital,...
January 31, 2010
Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration
Author(s): Salinas-Navarro M, Alarcón-Martínez L, Valiente-Soriano FJ, Jiménez-López M, Mayor-Torroglosa S, Avilés-Trigueros M, Villegas-Pérez MP,...
January 31, 2010
Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study
Author(s): Topouzis F, Harris A, Wilson MR, Koskosas A, Founti P, Yu F, Anastasopoulos E, Pappas T, Coleman AL Department of Ophthalmology, School...
November 30, 2009
Complex antibody profile changes in an experimental autoimmune glaucoma animal model
Author(s): Joachim SC, Grus FH, Kraft D, White-Farrar K, Barnes G, Barbeck M, Ghanaati S, Cao S, Li B, Wax MB Experimental Ophthalmology,...
October 31, 2009
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Glaucoma medications may harm the foetus and neonate
The Science behind the Tip Human data on adverse effects of glaucoma medications during pregnancy and lactation are sparse because the coincidence...
May 31, 2009
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Intraocular pressure is overestimated in eyes with a thick cornea
The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of Goldmann applanation tonometry (GAT)(1). The...
April 30, 2009
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A thin cornea is a risk factor for primary open-angle glaucoma
The Science behind the Tip Central corneal thickness (CCT) varies among individuals, the average CCT in the general population being approximately...
March 31, 2009
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Intraocular pressure is underestimated in eyes with a thin cornea
The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of applanation tonometry techniques such as...
February 28, 2009
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Visual field defects are filled-in by the brain
The Science behind the Tip Contrary to long held beliefs, cortical maps in the brain are not rigid. Extensive reorganization (i.e. brain remapping)...
January 31, 2009
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Pseudoexfoliation glaucoma has a strong genetic component
Publishing date: December 2008 The Science behind the Tip Pseudoexfoliation or exfoliation syndrome (PEX) is the most common identifiable condition...
December 31, 2008
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Chase the family of primary-open angle glaucoma patients
The Science behind the Tip Various modes of screening for primary open-angle glaucoma (POAG), i.e. different combinations of tonometry and...
November 30, 2008