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  • Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    The Science behind the Tip In contrast to underdiagnosis, which has been described in population-based studies as affecting 50% or more of glaucoma...

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    Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    The Science behind the Tip In contrast to underdiagnosis, which has been described in...

    Learn more...
  • Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    PURPOSE: The frequent use of optical coherence tomography increased the detection of peripapillary retinoschisis, which poses challenges in the...

    Learn more...
    Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    PURPOSE: The frequent use of optical coherence tomography increased the detection of...

    Learn more...
  • Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Purpose: To determine whether primary trabeculectomy or medical treatment produces better outcomes in terms of quality of life (QoL), clinical...

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    Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Purpose: To determine whether primary trabeculectomy or medical treatment produces better...

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  • Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway undeniably plays a pivotal role in the pathophysiology...

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    Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

    Learn more...
  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

    Learn more...
  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Peripapillary Retinoschisis in Glaucoma: A Systematic Review

NGP Paper

Peripapillary Retinoschisis in Glaucoma: A Systematic Review

PURPOSE: The frequent use of optical coherence tomography increased the detection of peripapillary retinoschisis, which poses challenges in the...

September 12, 2024

Treatment Outcomes Comparing the Paul and Baerveldt Glaucoma Implants After One Year of Follow-Up

NGP Paper

Treatment Outcomes Comparing the Paul and Baerveldt Glaucoma Implants After One Year of Follow-Up

PURPOSE: To compare efficacy and safety profiles of the Paul Glaucoma Implant (PGI) and Baerveldt Glaucoma Implant (BGI) in the treatment of...

June 16, 2024

Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

NGP Paper

Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate their impact on success rates. DESIGN: Systematic...

March 14, 2024

The relationship between multiple deprivation and severity of glaucoma at diagnosis

NGP Paper

The relationship between multiple deprivation and severity of glaucoma at diagnosis

BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

March 01, 2024

Risk Factors for Failure in Glaucoma Patients undergoing Microshunt Implantantion

NGP Paper

Risk Factors for Failure in Glaucoma Patients undergoing Microshunt Implantantion

PURPOSE: Evaluate risk factors for failure of Microshunt in glaucoma patients. DESIGN: Multicenter retrospective cohort study. METHODS:250 eyes...

December 17, 2023

Long-term Impact of Immediate Versus Delayed Treatment of Early Glaucoma: Results From the Early Manifest Glaucoma Trial

NGP Paper

Long-term Impact of Immediate Versus Delayed Treatment of Early Glaucoma: Results From the Early Manifest Glaucoma Trial

PURPOSE: To compare long-term visual outcomes in the 2 arms of the Early Manifest Glaucoma Trial (EMGT) and determine if delayed treatment was...

September 15, 2023

Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

NGP Paper

Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

June 30, 2023

The relationship between multiple deprivation and severity of glaucoma at diagnosis

NGP Paper

The relationship between multiple deprivation and severity of glaucoma at diagnosis

Author(s): Thai Ling Wong (1), Juan Lyn Ang (2), Sundeep Deol (2), Fiona Buckmaster (1), Alice D. McTrusty (1) and Andrew J. Tatham (1,2) 1 Centre...

March 30, 2023

Effect of trabeculectomy on the rate of progression of visual field damage

NGP Paper

Effect of trabeculectomy on the rate of progression of visual field damage

Author(s): Susanna Friederike Koenig (1,2), Giovanni Montesano (3,4), Clarissa Ern Hui Fang (5), David Paul Crabb (3), Hari Jayaram (5,4), Jonathan...

December 29, 2022

External Validation and Clinical Applicability of Two Optical Coherence Tomography-Based Risk Calculators for Detecting Glaucoma

NGP Paper

External Validation and Clinical Applicability of Two Optical Coherence Tomography-Based Risk Calculators for Detecting Glaucoma

Author(s): Néstor Ventura-Abreu (1), Marc Biarnés (2), Sofia Batlle-Ferrando (1), María Teresa Carrión-Donderis (1), Rafael Castro-Domínguez (1),...

September 30, 2022

Intravenous hypertonic saline to reduce intraocular pressure: the effect of splitting the bolus

NGP Paper

Intravenous hypertonic saline to reduce intraocular pressure: the effect of splitting the bolus

Author(s): Pia Inborr (1), Mika Harju (1), Tero T Kivelä (1) 1 Department of Ophthalmology, University of Helsinki and Helsinki University...

June 30, 2022

Intraocular Pressure and Its Relation to Ocular Geometry: Results From the Gutenberg Health Study

NGP Paper

Intraocular Pressure and Its Relation to Ocular Geometry: Results From the Gutenberg Health Study

Author(s): Esther M Hoffmann (1), Fidan Aghayeva (1), Felix M Wagner (1), Achim Fiess (1), Markus Nagler (2), Thomas Münzel (3,4), Philipp S Wild...

March 30, 2022

Virtual Reality-Based and Conventional Visual Field Examination Comparison in Healthy and Glaucoma Patients

NGP Paper

Virtual Reality-Based and Conventional Visual Field Examination Comparison in Healthy and Glaucoma Patients

Author(s): Jan Stapelfeldt (1), Serife Seda Kucur (1), Nina Huber (1), René Höhn (2), Raphael Sznitman (1) 1 ARTORG Center for Biomedical...

December 30, 2021

The glaucoma intensive treatment study: interim results from an ongoing longitudinal randomized clinical trial

NGP Paper

The glaucoma intensive treatment study: interim results from an ongoing longitudinal randomized clinical trial

Author(s): Boel Bengtsson (1), Christina Lindén (2), Anders Heijl (1), Sabina Andersson-Geimer (1), Johan Aspberg (1), Gauti Jóhannesson (2,3) 1...

September 30, 2021

Improving the Power of Glaucoma Neuroprotection Trials Using Existing Visual Field Data

NGP Paper

Improving the Power of Glaucoma Neuroprotection Trials Using Existing Visual Field Data

Author(s): Giovanni Montesano (1), Harry A Quigley (2), David P Crabb (3) 1 City, University of London Optometry and Visual Sciences (G.M.,...

June 30, 2021

Correlations Between Subjective Evaluation of Quality of Life, Visual Field Loss, and Performance in Simulated Activities of Daily Living in Glaucoma Patients

NGP Paper

Correlations Between Subjective Evaluation of Quality of Life, Visual Field Loss, and Performance in Simulated Activities of Daily Living in Glaucoma Patients

Author(s): Line Azoulay-Sebban (1), Zhanlin Zhao (2,3), Ariel Zenouda (1), Marco Lombardi (1,4), Emmanuel Gutman (1), Emmanuelle Brasnu (4),...

March 30, 2021

The Mont Blanc Study: The effect of altitude on intra ocular pressure and central corneal thickness

NGP Paper

The Mont Blanc Study: The effect of altitude on intra ocular pressure and central corneal thickness

Author(s): Carlo Bruttini (1), Alice Verticchio Vercellin (1,2,3), Catherine Klersy (4), Annalisa De Silvestri (4), Carmine Tinelli (4), Ivano Riva...

December 30, 2020

Mutations in SPATA13/ASEF2 Cause Primary Angle Closure Glaucoma

NGP Paper

Mutations in SPATA13/ASEF2 Cause Primary Angle Closure Glaucoma

Author(s): Naushin H Waseem (1), Sancy Low (2,3,4), Amna Z Shah (3), Deepa Avisetti (5), Pia Ostergaard (6), Michael Simpson (7), Katarzyna A...

September 30, 2020

Glaucoma Gel Implant Learning Curve in a Teaching Tertiary Hospital

NGP Paper

Glaucoma Gel Implant Learning Curve in a Teaching Tertiary Hospital

Author(s):* Raquel Esteves Marques (1,2), Nuno Pinto Ferreira (1,2), David Cordeiro Sousa (1,2,3), Joana Pinto (1,2), André Barata (1,2), Paula...

March 30, 2020

Intravenous Hypertonic Saline to Lower Intraocular Pressure in Ocular Hypertension and Primary Open-angle and Exfoliation Glaucoma

NGP Paper

Intravenous Hypertonic Saline to Lower Intraocular Pressure in Ocular Hypertension and Primary Open-angle and Exfoliation Glaucoma

Author(s): Pia Katriina Inborr (1), Mika Harju, Tero T Kivelä Department of Ophthalmology, Helsinki University Hospital and University of Helsinki,...

December 30, 2019

Prevalence of Treatment With Glaucoma Medication in Scotland, 2010-2017

NGP Paper

Prevalence of Treatment With Glaucoma Medication in Scotland, 2010-2017

Author(s): Alan P Rotchford (1), John Hughes (2), Pankaj Kumar Agarwal (3), Andrew J Tatham (3) Ophthalmology, Tennent Institute of Ophthalmology,...

July 20, 2019