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Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma
Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and...
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Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects
It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect...
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Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition
Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence...
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Not every ring scotoma is due to glaucoma
In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...
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Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression
Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...
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Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study
Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...
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Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study
Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...
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Childhood Glaucoma
SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...
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Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony
While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...
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Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains
Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...
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Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom
Purpose: A previously developed machine-learning approach with Kalman filtering technology...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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Early bleb revision usually results in successful resolution of hypotony maculopathy after trabeculectomy with mitomycin C
The Science behind the Tip Hypotony maculopathy is characterized by painless loss of vision usually more than three months after glaucoma...
January 31, 2019
Effects of Sex Hormones on Ocular Blood Flow and Intraocular Pressure in Primary Open-angle Glaucoma: A Review
Author(s): Patel P (1), Harris A (1), Toris C (2), Tobe L (1), Lang M (1), Belamkar A (1), Ng A (1), Verticchio Vercellin AC (3,4), Mathew S (1),...
January 31, 2019
Reduced Cerebrospinal Fluid Inflow to the Optic Nerve in Glaucoma
Author(s): Mathieu E (1,2,3), Gupta N (1,2,3,4,5), Paczka-Giorgi LA (1,2), Zhou X (1,2), Ahari A (1,2), Lani R (1), Hanna J (1,2,3), Yücel YH...
January 31, 2019
Next Generation Partnership SIG
IG Corner Editor: João Barbosa Breda Chair: Gauti Jóhannesson Co-chairs: Esther Hoffmann, Francesco Oddone, Anthony Khawaja 1. Update on ongoing...
January 24, 2019
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Children using topical corticosteroids for the treatment of allergic conjunctivitis must have their intraocular pressure regularly checked
The Science behind the Tip 30-40% of the population respond to topical steroids by increasing their IOP (1). A steroid response is commonly found...
December 31, 2018
Artificial intelligence and deep learning in ophthalmology
Author(s): Ting DSW (1), Pasquale LR (2), Peng L (3), Campbell JP (4), Lee AY (5), Raman R (6), Tan GSW (7), Schmetterer L (7,8,9,10), Keane PA...
December 31, 2018
Residual vision activation and the brain-eye-vascular triad: Dysregulation, plasticity and restoration in low vision and blindness - a review
Author(s): Sabel BA (1), Flammer J (2), Merabet LB (3) 1 Institute of Medical Psychology, Medical Faculty, Otto-von-Guericke University of...
December 31, 2018
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Exfoliative glaucoma is the most common type of secondary open angle glaucoma
Pearls Manager: Andrew Tatham It develops in approximately 15 to 26% of eyes with exfoliation syndrome within 5 years and frequently causes severe...
December 30, 2018
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The results of trabeculectomy with mitomycin C are significantly improved in children with glaucoma secondary to juvenile idiopathic arthritis if they are on immune-modulatory treatment
The Science behind the Tip Juvenile idiopathic arthritis (JIA) is the most common systemic disease associated with childhood anterior uveitis....
November 30, 2018
Familial Risks of Glaucoma in the Population of Sweden
Author(s): Li X (1), Sundquist J (1,2,3), Zöller B (1), Sundquist K (1,2,3) 1 Center for Primary Health Care Research, Lund University, Sweden. 2...
November 30, 2018
Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma
Author(s): Singh LN (1), Crowston JG (2), Lopez Sanchez MIG (2), Van Bergen NJ (2), Kearns LS (2), Hewitt AW (2,3), Yazar S (4,5), Mackey DA (4),...
November 30, 2018
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Do you know how to stage an angle closure?
Pearls Manager: Andrew Tatham Primary Angle-Closure Suspect (PACS) - Two or more quadrants of iridotrabecular contact (lTC), normal IOP, no PAS, no...
November 23, 2018
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Microperimetry may be a more sensitive method of detecting a small glaucomatous defect close to fixation, than standard automated perimetry and OCT analysis of the retinal nerve fibre layer (RNFL)
The Science behind the Tip Microperimetry is a form of fundus-tracking perimetry that can detect reduced retinal sensitivity close to fixation more...
October 31, 2018
The Magnitude of IOP Elevation Associated with Eye Rubbing
Author(s): Turner DC (1), Girkin CA (2), Downs JC (3) 1 Department of Vision Sciences, School of Optometry, University of Alabama at Birmingham,...
October 31, 2018
Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma
Author(s): Bosco A(1), Anderson SR(2), Breen KT(2), Romero CO(2), Steele MR(2), Chiodo VA(3), Boye SL(3), Hauswirth WW(3), Tomlinson S(4), Vetter...
October 31, 2018
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When to perform a prophylactic iridotomy?
Pearls Manager: Andrew Tatham An international group of experts reached a consensus that 2 quadrants or more of ITC is an indication for...
October 22, 2018
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A glaucoma drainage device may be more effective than trabeculectomy in lowering IOP after keratoplasty, but is more likely to result in graft failure
The Science behind the Tip A well-controlled intraocular pressure (IOP) after penetrating keratoplasty (PK) is essential for graft survival and to...
September 30, 2018
Structural reversal of disc cupping after trabeculectomy alters Bruch's membrane opening-based parameters to assess neuroretinal rim
Author(s): Gietzelt C (1), Lemke J (1), Schaub F (1), Hermann MM (1), Dietlein TS (1), Cursiefen C (1), Enders P (2), Heindl LM (1) 1 Department of...
September 30, 2018
Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma
Author(s): MacGregor S (1), Ong JS (2), An J (2), Han X (2), Zhou T (3), Siggs OM (3), Law MH (2), Souzeau E (3), Sharma S (3), Lynn DJ (4,5,6),...
September 30, 2018
Tolerable rates of visual field progression in a population-based sample of patients with glaucoma
Author(s): Salonikiou A (1), Founti P (1,2), Kilintzis V (1), Antoniadis A (1), Anastasopoulos E (1), Pappas T (1), Raptou A (1), Topouzis F (1) 1...
July 31, 2018
Nogo-A inactivation improves visual plasticity and recovery after retinal injury
Author(s): Mdzomba JB (1), Jordi N (2), Rodriguez L (1), Joly S (1), Bretzner F (3), Pernet V (4) 1 CUO-Recherche, Centre de recherche du CHU de...
July 31, 2018
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When determining a therapeutic approach to a patient with glaucoma, the life expectancy of the patient needs to be considered
The Science behind the Tip Patients who present with early glaucoma who have a short life expectancy are unlikely to go blind from glaucoma in...
June 30, 2018
Progression of Primary Open-Angle Glaucoma in Diabetic and Nondiabetic Patients
Author(s): Hou H (1), Shoji T (2), Zangwill LM (1), Moghimi S (3), Saunders LJ (1), Hasenstab K (1), Ghahari E (1), Manalastas PIC (1), Akagi T...
June 30, 2018
Glaucoma pathogenesis and neurotrophins: Focus on the Molecular and Genetic basis for Therapeutic prospects
Author(s): Chitranshi N (1), Dheer Y (1), Abbasi M (1), You Y (2), Graham SL (1), Gupta V (1) 1 Faculty of Medicine and Health Sciences, Macquarie...
June 30, 2018
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The insertion of a punctal plug improves ocular comfort and results in a modest reduction of IOP in patients with glaucoma who are using topical medication
The Science behind the Tip Patients with ocular hypertension and chronic glaucoma have a higher prevalence of ocular surface disease (OSD) than...
May 31, 2018