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  • In Vitro Analysis of Pressure Resistance in the Paul Glaucoma Implant and Ahmed ClearPath 250 With and Without Polypropylene Thread Inside the Tube

    Purpose: Pressure resistance characteristics of the Paul glaucoma implant (PGI) and Ahmed ClearPath 250 (ACP), with and without the insertion of...

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    In Vitro Analysis of Pressure Resistance in the Paul Glaucoma Implant and Ahmed ClearPath 250 With and Without Polypropylene Thread Inside the Tube

    In Vitro Analysis of Pressure Resistance in the Paul Glaucoma Implant and Ahmed ClearPath 250 With and Without Polypropylene Thread Inside the Tube

    Purpose: Pressure resistance characteristics of the Paul glaucoma implant (PGI) and Ahmed...

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  • The Impact of Baseline Intraocular Pressure on Initial Treatment Response in the LiGHT Trial: Selective Laser Trabeculoplasty versus Medication

    Purpose: The Laser in Glaucoma and Ocular Hypertension Trial demonstrated the efficacy and safety of selective laser trabeculoplasty (SLT) compared...

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    The Impact of Baseline Intraocular Pressure on Initial Treatment Response in the LiGHT Trial: Selective Laser Trabeculoplasty versus Medication

    The Impact of Baseline Intraocular Pressure on Initial Treatment Response in the LiGHT Trial: Selective Laser Trabeculoplasty versus Medication

    Purpose: The Laser in Glaucoma and Ocular Hypertension Trial demonstrated the efficacy and safety...

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  • Insertion of an intraluminal ripcord suture to prevent early post operative hypotony

    Hypotony is a common complication associated with the implantation of various unvalved glaucoma drainage devices. To reduce the risk of this...

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    Insertion of an intraluminal ripcord suture to prevent early post operative hypotony

    Insertion of an intraluminal ripcord suture to prevent early post operative hypotony

    Hypotony is a common complication associated with the implantation of various unvalved glaucoma...

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  • Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned people. This sociological concept is a result of...

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    Fatal beauty: which cosmetics are your glaucoma patients using?

    Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transection

Clinical paper of the month

Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transection

Author(s): Levkovitch-Verbin H, Sadan O, Vander S, Rosner M, Barhum Y, Melamed E, Offen D, Melamed S. Goldschleger Eye Institute, Sheba Medical...

January 31, 2011

Reversal of retinal ganglion cell dysfunction after surgical reduction of intraocular pressure

Experimental Paper of the Month

Reversal of retinal ganglion cell dysfunction after surgical reduction of intraocular pressure

Author(s): Sehi M, Grewal DS, Goodkin ML, Greenfield DS. Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller...

January 31, 2011

Small field depressions can be more worrying than large ones

Tip of the month

Small field depressions can be more worrying than large ones

The Science behind the Tip Much of the decision making in modern glaucoma practice is based on automated visual field test results. Careful...

December 31, 2010

Predicting visual function from the measurements of retinal nerve fiber layer structure

Clinical paper of the month

Predicting visual function from the measurements of retinal nerve fiber layer structure

Author(s): Zhu H, Crabb DP, Schlottmann PG, Lemij HG, Reus NJ, Healey PR, Mitchell P, Ho T, Garway-Heath DF Department of Optometry and Visual...

December 31, 2010

Canadian Glaucoma Study: 3. Impact of risk factors and intraocular pressure reduction on the rates of visual field change

Clinical paper of the month

Canadian Glaucoma Study: 3. Impact of risk factors and intraocular pressure reduction on the rates of visual field change

Author(s): Chauhan BC, Mikelberg FS, Artes PH, Balazsi AG, LeBlanc RP, Lesk MR, Nicolela MT, Trope GE; Canadian Glaucoma Study Group Collaborators...

November 30, 2010

Qualitative and quantitative morphologic changes in the vasculature and extracellular matrix of the prelaminar optic nerve head in eyes with POAG

Experimental Paper of the Month

Qualitative and quantitative morphologic changes in the vasculature and extracellular matrix of the prelaminar optic nerve head in eyes with POAG

Author(s): Tektas OY, Lütjen-Drecoll E, Scholz M Institute of Anatomy II, University of Erlangen-Nuremberg, Erlangen, Germany....

November 30, 2010

The cataract surgeon should be informed that the patient has pseudo-exfoliation syndrome

Tip of the month

The cataract surgeon should be informed that the patient has pseudo-exfoliation syndrome

The Science behind the Tip Although the diagnosis of pseudo-exfoliation syndrome (PEX) with a fully dilated pupil in an elderly patient should pose...

October 31, 2010

Incidence of glaucomatous visual field loss: a ten-year follow-up from the Rotterdam Study

Clinical paper of the month

Incidence of glaucomatous visual field loss: a ten-year follow-up from the Rotterdam Study

Author(s): Czudowska MA, Ramdas WD, Wolfs RC, Hofman A, De Jong PT, Vingerling JR, Jansonius NM Department of Epidemiology, Erasmus Medical Center,...

October 31, 2010

Functional MRI signal changes in primary visual cortex corresponding to the central normal visual field of patients with primary open-angle glaucoma

Experimental Paper of the Month

Functional MRI signal changes in primary visual cortex corresponding to the central normal visual field of patients with primary open-angle glaucoma

Author(s): Qing G, Zhang S, Wang B, Wang N Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology...

October 31, 2010

If conservative measures are unsuccessful in the management of malignant glaucoma, phaco with IOL combined with posterior capsulotomy and anterior vitrectomy usually is

Tip of the month

If conservative measures are unsuccessful in the management of malignant glaucoma, phaco with IOL combined with posterior capsulotomy and anterior vitrectomy usually is

The Science behind the Tip Malignant glaucoma in a phakic eye typically follows incisional surgery for primary angle-closure glaucoma. Shallowing...

September 30, 2010

Anthropometric measures and their relation to incident primary open-angle glaucoma

Clinical paper of the month

Anthropometric measures and their relation to incident primary open-angle glaucoma

Author(s): Pasquale LR, Willett WC, Rosner BA, Kang JH Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary,...

September 30, 2010

Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve

Experimental Paper of the Month

Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve

Author(s): Dahlmann-Noor A, Vijay S, Jayaram H, Limb A, Khaw PT. The 3 most common causes of visual impairment and legal blindness in developed...

September 30, 2010

Effect of sleeping in a head-up position on intraocular pressure in patients with glaucoma

Clinical paper of the month

Effect of sleeping in a head-up position on intraocular pressure in patients with glaucoma

Author(s): Buys YM, Alasbali T, Jin YP, Smith M, Gouws P, Geffen N, Flanagan JG, Shapiro CM, Trope GE Department of Ophthalmology and Vision...

August 31, 2010

Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility

Experimental Paper of the Month

Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility

Author(s): Writing Committee fot the Normal Tension Glaucoma Genetic Study Group of Japan Glaucoma Society, Meguro A, Inoko H, Ota M, Mizuki N,...

August 31, 2010

Clinical classification of childhood glaucomas

Clinical paper of the month

Clinical classification of childhood glaucomas

Author(s): Yeung HH, Walton DS Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA....

July 31, 2010

Mitochondrial damage in the trabecular meshwork of patients with glaucoma

Experimental Paper of the Month

Mitochondrial damage in the trabecular meshwork of patients with glaucoma

Author(s): Izzotti A, Saccà SC, Longobardi M, Cartiglia C. Department of Health Sciences, University of Genoa, Genoa, Italy. izzotti@unige.it...

July 31, 2010

In patients with chronic angle-closure glaucoma and cataract, phacoemulsification with IOL implantation usually results in IOP control up to 2 years after surgery

Tip of the month

In patients with chronic angle-closure glaucoma and cataract, phacoemulsification with IOL implantation usually results in IOP control up to 2 years after surgery

The Science behind the Tip An anteriorly positioned and thickened lens plays an important role in the pathogenesis of anterior chamber shallowing...

June 30, 2010

Effect of patient's life expectancy on the cost-effectiveness of treatment for ocular hypertension

Clinical paper of the month

Effect of patient's life expectancy on the cost-effectiveness of treatment for ocular hypertension

Author(s): Kymes SM, Plotzke MR, Kass MA, Boland MV, Gordon MO OBJECTIVE: To assess the influence of expected life span on the cost-effectiveness...

June 30, 2010

Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration

Experimental Paper of the Month

Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration

Author(s): Baltan S, Inman DM, Danilov CA, Morrison RS, Calkins DJ, Horner PJ. We tested the hypothesis that glaucoma disrupts electrophysiological...

June 30, 2010

Measurement of central corneal thickness is essential to ensure optimal management of glaucoma patients

Tip of the month

Measurement of central corneal thickness is essential to ensure optimal management of glaucoma patients

The Science behind the Tip The measurement of central corneal thickness (CCT) has emerged as an important parameter to determine in all patients...

May 31, 2010

Delaying Treatment of Ocular Hypertension: the Ocular Hypertension Treatment Study

Clinical paper of the month

Delaying Treatment of Ocular Hypertension: the Ocular Hypertension Treatment Study

Author(s): Michael A. Kass, MD; Mae O. Gordon, PhD; Feng Gao, PhD; Dale K. Heuer, MD; Eve J. Higginbotham, MD; Chris A. Johnson, PhD; John K....

May 31, 2010

Neuroprotective Effects of Intravitreal Mesenchymal Stem Cell Transplantation in Experimental Glaucoma

Experimental Paper of the Month

Neuroprotective Effects of Intravitreal Mesenchymal Stem Cell Transplantation in Experimental Glaucoma

Author(s): Thomas V. Johnson(1,2,3) Natalie D. Bull(1,2) David P. Hunt(1), Nephtali Marina(1), Stanislav I. Tomarev(3), Keith R. Martin(1) Centre...

May 31, 2010

Disc Haemorrhages

Tip of the month

Disc Haemorrhages

The Science behind the Tip Although described most commonly in normal tension glaucoma, optic disc haemorrhages may occur in all forms of glaucoma....

April 30, 2010

When should neuroradiological imaging be undertaken in patients with normal tension glaucoma?

Tip of the month

When should neuroradiological imaging be undertaken in patients with normal tension glaucoma?

The Science behind the Tip Clinicians must remain vigilant to detect intracranial pathology in patients with normal tension glaucoma. Most patients...

March 31, 2010

Simvastatin and Disease Stabilization in Normal Tension Glaucoma: A Cohort Study.

Clinical paper of the month

Simvastatin and Disease Stabilization in Normal Tension Glaucoma: A Cohort Study.

Author(s): Leung DY, Li FC, Kwong YY, Tham CC, Chi SC, Lam DS. Department of Ophthalmology and Visual Sciences, The Chinese University of Hong...

March 31, 2010