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  • Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    The Science behind the Tip In contrast to underdiagnosis, which has been described in population-based studies as affecting 50% or more of glaucoma...

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    Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    The Science behind the Tip In contrast to underdiagnosis, which has been described in...

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  • Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    PURPOSE: The frequent use of optical coherence tomography increased the detection of peripapillary retinoschisis, which poses challenges in the...

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    Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    PURPOSE: The frequent use of optical coherence tomography increased the detection of...

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  • Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Purpose: To determine whether primary trabeculectomy or medical treatment produces better outcomes in terms of quality of life (QoL), clinical...

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    Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Purpose: To determine whether primary trabeculectomy or medical treatment produces better...

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  • Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway undeniably plays a pivotal role in the pathophysiology...

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    Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Long-Term Follow-up in Preperimetric Open-Angle Glaucoma: Progression Rates and Associated Factors

Clinical paper of the month

Long-Term Follow-up in Preperimetric Open-Angle Glaucoma: Progression Rates and Associated Factors

Author(s): Kim KE(1), Jeoung JW(2), Kim DM(1), Ahn SJ(3), Park KH(1), Kim SH(4) 1 Department of Ophthalmology, Seoul National University College of...

February 28, 2015

The impact of lack of government insured routine eye examinations on the incidence of self-reported glaucoma, cataracts and vision loss

Clinical paper of the month

The impact of lack of government insured routine eye examinations on the incidence of self-reported glaucoma, cataracts and vision loss

Author(s): Chan CH (1), Trope GE (2), Badley EM (3), Buys Y (4), Jin YP (5) 1 Division of Health Care and Outcomes Research, Toronto Western...

January 31, 2015

Clinical outcomes in cytomegalovirus-positive posner-schlossman syndrome patients treated with topical ganciclovir therapy

Clinical paper of the month

Clinical outcomes in cytomegalovirus-positive posner-schlossman syndrome patients treated with topical ganciclovir therapy

Author(s): Su CC(1), Hu FR(2), Wang TH(2), Huang JY(2), Yeh PT(2), Lin CP(2), Wang IJ(3) 1 Department of Ophthalmology, National Taiwan University...

December 31, 2014

Nocturnal systemic hypotension increases the risk of glaucoma progression

Clinical paper of the month

Nocturnal systemic hypotension increases the risk of glaucoma progression

Author(s): Charlson ME, de Moraes CG, Link A, Wells MT, Harmon G, Peterson JC, Ritch R, Liebmann JM 1 Center for Integrative Medicine, Weill...

November 30, 2014

Optic Nerve Head Deformation in Glaucoma: The Temporal Relationship between Optic Nerve Head Surface Depression and Retinal Nerve Fiber Layer Thinning

Clinical paper of the month

Optic Nerve Head Deformation in Glaucoma: The Temporal Relationship between Optic Nerve Head Surface Depression and Retinal Nerve Fiber Layer Thinning

Author(s): Xu G(1), Weinreb RN(2), Leung CK(3) 1 Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong,...

October 31, 2014

Rates of retinal nerve fiber layer thinning in glaucoma suspect eyes

Clinical paper of the month

Rates of retinal nerve fiber layer thinning in glaucoma suspect eyes

Author(s): Miki A(1), Medeiros FA(2), Weinreb RN(2), Jain S(3), He F(3), Sharpsten L(2), Khachatryan N(2), Hammel N(2), Liebmann JM(4), Girkin...

September 30, 2014

The effect of positional changes on intraocular pressure during sleep in patients with and without glaucoma

Clinical paper of the month

The effect of positional changes on intraocular pressure during sleep in patients with and without glaucoma

Author(s): Lazzaro EC(1), Mallick A, Singh M, Reich I, Elmann S, Stefanov DG, Lazzaro DR. 1 Department of Ophthalmology - Scientific Computing...

July 31, 2014

Three-year Treatment Outcomes in the Ahmed Baerveldt Comparison Study

Clinical paper of the month

Three-year Treatment Outcomes in the Ahmed Baerveldt Comparison Study

Author(s): Barton K(1), Feuer WJ(2), Budenz DL(3), Schiffman J(2), Costa VP(4), Godfrey DG(5), Buys YM(6); Ahmed Baerveldt Comparison Study Group 1...

June 30, 2014

Effect of Focal Lamina Cribrosa Defect on Glaucomatous Visual Field Progression

Clinical paper of the month

Effect of Focal Lamina Cribrosa Defect on Glaucomatous Visual Field Progression

Author(s): Faridi OS(1), Park SC(2), Kabadi R(3), Su D(1), De Moraes CG(4), Liebmann JM(4), Ritch R(5) 1 Moise and Chella Safra Advanced Ocular...

May 31, 2014

Intraocular pressure fluctuation and glaucoma progression: what do we know?

Clinical paper of the month

Intraocular pressure fluctuation and glaucoma progression: what do we know?

Author(s): Leidl MC(1), Choi CJ, Syed ZA, Melki SA. 1 Nassau University Medical Center, East Meadow, New York, USA. While mean intraocular pressure...

April 30, 2014

The Potential Association Between Postmenopausal Hormone Use and Primary Open-Angle Glaucoma

Clinical paper of the month

The Potential Association Between Postmenopausal Hormone Use and Primary Open-Angle Glaucoma

Author(s): Newman-Casey PA(1), Talwar N(1), Nan B(2), Musch DC(3), Pasquale LR(4), Stein JD(5). 1 Department of Ophthalmology and Visual Sciences,...

March 31, 2014

The 5-Year Incidence of Bleb-Related Infection and Its Risk Factors after Filtering Surgeries with Adjunctive Mitomycin C: Collaborative Bleb-Related Infection Incidence and Treatment Study 2

Clinical paper of the month

The 5-Year Incidence of Bleb-Related Infection and Its Risk Factors after Filtering Surgeries with Adjunctive Mitomycin C: Collaborative Bleb-Related Infection Incidence and Treatment Study 2

Author(s): Yamamoto T (1), Sawada A (2), Mayama C (3), Araie M (3), Ohkubo S (4), Sugiyama K4, Kuwayama Y (5); The Collaborative Bleb-Related...

January 31, 2014

Relationship between Preferred Sleeping Position and Asymmetric Visual-field Loss in Open-angle Glaucoma Patients

Clinical paper of the month

Relationship between Preferred Sleeping Position and Asymmetric Visual-field Loss in Open-angle Glaucoma Patients

Author(s): Kim KN(1), Jeoung JW(2), Park KH(3), Kim DM(4), Ritch R(5) 1 Department of Ophthalmology, Chungnam National University Hospital,...

January 31, 2014

Does optic nerve head surface topography change prior to loss of retinal nerve fiber layer thickness: a test of the site of injury hypothesis in experimental glaucoma

Clinical paper of the month

Does optic nerve head surface topography change prior to loss of retinal nerve fiber layer thickness: a test of the site of injury hypothesis in experimental glaucoma

Author(s): Fortune B, Reynaud J, Wang L, Burgoyne CF. Discoveries in Sight Research Laboratories, Devers Eye Institute, and Legacy Research...

December 31, 2013

Pathogenesis and clinical implications of optic disk hemorrhage in glaucoma

Clinical paper of the month

Pathogenesis and clinical implications of optic disk hemorrhage in glaucoma

Author(s): Suh MH, Park KH. Department of Ophthalmology, Haeundae Paik Hospital, Busan, Korea; Department of Ophthalmology, Inje University College...

November 30, 2013

Lifetime Risk of Blindness in Open-Angle Glaucoma

Clinical paper of the month

Lifetime Risk of Blindness in Open-Angle Glaucoma

Author(s): Peters D, Bengtsson B, Heijl A Department of Ophthalmology, Lund University, Skåne University Hospital, Malmö, Sweden. Electronic...

October 31, 2013

The Ahmed Versus Baerveldt Study: Three-Year Treatment Outcomes

Clinical paper of the month

The Ahmed Versus Baerveldt Study: Three-Year Treatment Outcomes

Author(s): Christakis PG, Tsai JC, Kalenak JW, Zurakowski D, Cantor LB, Kammer JA, Ahmed II. Department of Ophthalmology and Vision Sciences,...

September 30, 2013

Rho-associated kinase inhibitors: A novel glaucoma therapy

Clinical paper of the month

Rho-associated kinase inhibitors: A novel glaucoma therapy

Author(s): Inoue T, Tanihara H. Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan....

July 31, 2013

Prevalence and Severity of Undetected Manifest Glaucoma: Results from the Early Manifest Glaucoma Trial Screening

Clinical paper of the month

Prevalence and Severity of Undetected Manifest Glaucoma: Results from the Early Manifest Glaucoma Trial Screening

Author(s): Heijl A, Bengtsson B, Oskarsdottir SE. Lund University, Department of Clinical Sciences Malmö, Ophthalmology, Skåne University Hospital,...

June 30, 2013

The eye and the heart

Clinical paper of the month

The eye and the heart

Author(s): Flammer J, Konieczka K, Bruno R M, Virdis A, Flammer A J, Taddei S The vasculature of the eye and the heart share several common...

May 31, 2013

How Does Glaucoma Look?: Patient Perception of Visual Field Loss

Clinical paper of the month

How Does Glaucoma Look?: Patient Perception of Visual Field Loss

Author(s): Crabb DP, Smith ND, Glen FC, Burton R, Garway-Heath DF Department of Optometry and Visual Science, City University London, London,...

April 30, 2013

Treatment Outcomes in Malignant Glaucoma

Clinical paper of the month

Treatment Outcomes in Malignant Glaucoma

Author(s): Dave P, Senthil S, Rao HL, Garudadri CS. L. V. Prasad Eye Institute, Hyderabad, India. PURPOSE: To report treatment outcomes in...

March 31, 2013

Balance control in glaucoma

Clinical paper of the month

Balance control in glaucoma

Author(s): Kotecha A, Richardson G, Chopra R, Fahy RT, Garway-Heath DF, Rubin GS Department of Visual Neuroscience, University College London (UCL)...

January 31, 2013

Factors that influence standard automated perimetry test results in glaucoma: test reliability, technician experience, time of day, and season

Clinical paper of the month

Factors that influence standard automated perimetry test results in glaucoma: test reliability, technician experience, time of day, and season

Author(s): Junoy Montolio FG, Wesselink C, Gordijn M, Jansonius NM Department of Ophthalmology, University Medical Center Groningen, University of...

December 31, 2012

Retinal Vessel Caliber Is Associated with the 10-year Incidence of Glaucoma: The Blue Mountains Eye Study

Clinical paper of the month

Retinal Vessel Caliber Is Associated with the 10-year Incidence of Glaucoma: The Blue Mountains Eye Study

Author(s): Kawasaki R, Wang JJ, Rochtchina E, Lee AJ, Wong TY, Mitchell P. Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital,...

November 30, 2012