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Tip: Not every peripapillary hemorrhage is a sign for glaucoma
The Science behind the Tip Most of the time, disc hemorrhages in patients with glaucoma are...
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The Factors Affecting the Stability of IOP Homeostasis
Purpose: Shear-induced nitric oxide (NO) production by Schlemm's canal (SC) endothelial cells...
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Short-term Detection of Fast Progressors in Glaucoma: The Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study
Purpose: To evaluate the performance of an intensive, clustered testing approach in identifying...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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Exogenous influences on intraocular pressure
Author(s): Kim YW (1), Park KH (2) 1 Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea. 2 Ophthalmology, Seoul National...
May 31, 2019
Rapamycin Removes Damaged Mitochondria and Protects Human Trabecular Meshwork (TM-1) Cells from Chronic Oxidative Stress
Author(s): He JN (1,2), Zhang SD (3), Qu Y (2), Wang HL (2), Tham CC (1), Pang CP (1), Chu WK (4) 1 Department of Ophthalmology and Visual...
May 31, 2019
Angle Closure SIG
SIG Corner Editor: João Barbosa Breda Chair: John Thygesen Co-chair: Gus Gazzard 1. Goals and Activities of the SIG The Angle Closure SIG promotes...
May 30, 2019
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Glaucoma and intraocular bleeding
Pearls Manager: Andrew Tatham Either acute bleeding in the anterior chamber or long standing blood in the vitreous of any source can cause IOP...
May 30, 2019
Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial
Author(s): Gazzard G (1), Konstantakopoulou E (2), Garway-Heath D (2), Garg A (2), Vickerstaff V (3), Hunter R (4), Ambler G (5), Bunce C (6),...
April 30, 2019
Border Tissue Morphology is Spatially Associated with Focal Lamina Cribrosa Defect and Deep-Layer Microvasculature Dropout in Open-Angle Glaucoma
Author(s): Han JC (1), Choi JH (1), Park DY (1), Lee EJ (1), Kee C (2) 1 Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan...
April 30, 2019
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Management of glaucoma during pregnancy
Pearls Manager: Andrew Tatham Women with glaucoma of child bearing age should be informed about the possible need to modify treatment during...
April 30, 2019
Imaging SIG
SIG Corner Editor: João Barbosa Breda Chair: Hans LemijCo-chair: David Garway-Heath 1. Goals and Activities of the SIG The Imaging SIG’s main...
April 01, 2019
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Ocular coherence tomography (OCT) should be used cautiously in the context of uveitic glaucoma
The Science behind the Tip Patients with uveitis have a heightened risk of developing secondary glaucoma. Ocular Coherence Tomography (OCT) imaging...
March 31, 2019
Visual Crowding in Glaucoma
Author(s): Ogata NG (1), Boer ER (2), Daga FB (1), Jammal AA (1), Stringham JM (1), Medeiros FA (1) 1 Duke Eye Center, Department of Ophthalmology,...
March 31, 2019
Artificial intelligence and deep learning in ophthalmology
Author(s): Ting DSW (1), Pasquale LR (2), Peng L (3), Campbell JP (4), Lee AY (5), Raman R (6), Tan GSW (7), Schmetterer L (7,8,9,10), Keane PA...
March 31, 2019
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Pigmentary glaucoma
Pearls Manager: Andrew Tatham Pigmentary glaucoma represents 1 to 1.5% of all glaucoma cases. It is more common in Caucasian myopic men and is...
March 30, 2019
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Depression may follow a diagnosis of chronic glaucoma, but depressive symptoms are less likely to be present one year later
The Science behind the Tip It is common for a newly-diagnosed patient with glaucoma to experience symptoms of depression (1,2). Patients who are...
March 01, 2019
The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Inter-eye Comparison Study
Author(s): Choi JH (1), Han JC, Kee C 1 Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,...
February 28, 2019
Identification of Candidate miRNA Biomarkers for Glaucoma
Author(s): Hindle AG1, Thoonen R2, Jasien JV (3), Grange RMH (1), Amin K (4), Wise J (4), Ozaki M (5), Ritch R (3), Malhotra R (2), Buys ES (1) 1...
February 28, 2019
Care Delivery SIG
SIG Corner Editor: João Barbosa Breda Chair: Anton B. Hommer Co-chair: Gabor Holló Update on ongoing projects The goal of this SIG is to get a...
February 28, 2019
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How to perform Goldmann applanation tonometry in patients with significant regular corneal astigmatism
Pearls Manager: Andrew Tatham When performing Goldmann applanation tonometry in patients with significant regular corneal astigmatism (>3...
February 20, 2019
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Early bleb revision usually results in successful resolution of hypotony maculopathy after trabeculectomy with mitomycin C
The Science behind the Tip Hypotony maculopathy is characterized by painless loss of vision usually more than three months after glaucoma...
January 31, 2019
Effects of Sex Hormones on Ocular Blood Flow and Intraocular Pressure in Primary Open-angle Glaucoma: A Review
Author(s): Patel P (1), Harris A (1), Toris C (2), Tobe L (1), Lang M (1), Belamkar A (1), Ng A (1), Verticchio Vercellin AC (3,4), Mathew S (1),...
January 31, 2019
Reduced Cerebrospinal Fluid Inflow to the Optic Nerve in Glaucoma
Author(s): Mathieu E (1,2,3), Gupta N (1,2,3,4,5), Paczka-Giorgi LA (1,2), Zhou X (1,2), Ahari A (1,2), Lani R (1), Hanna J (1,2,3), Yücel YH...
January 31, 2019
Next Generation Partnership SIG
IG Corner Editor: João Barbosa Breda Chair: Gauti Jóhannesson Co-chairs: Esther Hoffmann, Francesco Oddone, Anthony Khawaja 1. Update on ongoing...
January 24, 2019
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Children using topical corticosteroids for the treatment of allergic conjunctivitis must have their intraocular pressure regularly checked
The Science behind the Tip 30-40% of the population respond to topical steroids by increasing their IOP (1). A steroid response is commonly found...
December 31, 2018
Artificial intelligence and deep learning in ophthalmology
Author(s): Ting DSW (1), Pasquale LR (2), Peng L (3), Campbell JP (4), Lee AY (5), Raman R (6), Tan GSW (7), Schmetterer L (7,8,9,10), Keane PA...
December 31, 2018
Residual vision activation and the brain-eye-vascular triad: Dysregulation, plasticity and restoration in low vision and blindness - a review
Author(s): Sabel BA (1), Flammer J (2), Merabet LB (3) 1 Institute of Medical Psychology, Medical Faculty, Otto-von-Guericke University of...
December 31, 2018
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Exfoliative glaucoma is the most common type of secondary open angle glaucoma
Pearls Manager: Andrew Tatham It develops in approximately 15 to 26% of eyes with exfoliation syndrome within 5 years and frequently causes severe...
December 30, 2018