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  • Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate their impact on success rates. DESIGN: Systematic...

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    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate...

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  • A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health conditions in retinal images and expediting the...

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    A foundation model for generalizable disease detection from retinal images

    A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health...

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  • Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation compares medical and surgical management...

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    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation...

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  • Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT) has brought attention to rare side effects such as...

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    Beware of acute corneal oedema after SLT in selected patients

    Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT)...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Glaucoma medications may harm the foetus and neonate

Tip of the month

Glaucoma medications may harm the foetus and neonate

The Science behind the Tip Human data on adverse effects of glaucoma medications during pregnancy and lactation are sparse because the coincidence...

May 31, 2009

Intraocular pressure is overestimated in eyes with a thick cornea

Tip of the month

Intraocular pressure is overestimated in eyes with a thick cornea

The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of Goldmann applanation tonometry (GAT)(1). The...

April 30, 2009

A thin cornea is a risk factor for primary open-angle glaucoma

Tip of the month

A thin cornea is a risk factor for primary open-angle glaucoma

The Science behind the Tip Central corneal thickness (CCT) varies among individuals, the average CCT in the general population being approximately...

March 31, 2009

Intraocular pressure is underestimated in eyes with a thin cornea

Tip of the month

Intraocular pressure is underestimated in eyes with a thin cornea

The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of applanation tonometry techniques such as...

February 28, 2009

Visual field defects are filled-in by the brain

Tip of the month

Visual field defects are filled-in by the brain

The Science behind the Tip Contrary to long held beliefs, cortical maps in the brain are not rigid. Extensive reorganization (i.e. brain remapping)...

January 31, 2009

Pseudoexfoliation glaucoma has a strong genetic component

Tip of the month

Pseudoexfoliation glaucoma has a strong genetic component

Publishing date: December 2008 The Science behind the Tip Pseudoexfoliation or exfoliation syndrome (PEX) is the most common identifiable condition...

December 31, 2008

Chase the family of primary-open angle glaucoma patients

Tip of the month

Chase the family of primary-open angle glaucoma patients

The Science behind the Tip Various modes of screening for primary open-angle glaucoma (POAG), i.e. different combinations of tonometry and...

November 30, 2008

Intraocular pressure should be monitored after an acute episode of angle-closure

Tip of the month

Intraocular pressure should be monitored after an acute episode of angle-closure

The Science behind the Tip Treatment of acute attacks of angle-closure glaucoma induced by pupillary block is based on medical therapy aiming at...

October 31, 2008

Topical medication may accelerate cataract formation

Tip of the month

Topical medication may accelerate cataract formation

The Science behind the Tip A number of large studies have linked use of topical glaucoma medication with increased risk of nuclear cataract, the...

September 30, 2008

Closing the eyes as an alternative for nasolacrimal duct occlusion

Tip of the month

Closing the eyes as an alternative for nasolacrimal duct occlusion

The Science behind the Tip The Science behind the Tip Manual nasolacrimal occlusion after eye drop instillation is often taught to glaucoma...

June 30, 2008

There is no significant association between use of β-blockers and depression

Tip of the month

There is no significant association between use of β-blockers and depression

The Science behind the Tip The Science behind the Tip The methodological quality of early studies of the association of systemic or topical...

May 31, 2008

Trabeculectomy significantly increases the incidence of cataract formation

Tip of the month

Trabeculectomy significantly increases the incidence of cataract formation

The Science behind the Tip The Science behind the Tip It is widely acknowledged that trabeculectomy (TRAB) accelerates cataract formation. The...

April 30, 2008

Concomitant therapy with Cosopt® and Diamox® is not useful

Tip of the month

Concomitant therapy with Cosopt® and Diamox® is not useful

The Science behind the Tip Although the ß-blocker timolol and the topical carbonic anhydrase inhibitor (CAI) dorzolamide both act by decreased...

March 31, 2008

Rate of false positive answers is the only reliable reliability parameter in computerized perimetry

Tip of the month

Rate of false positive answers is the only reliable reliability parameter in computerized perimetry

The Science behind the Tip In computerized perimetry patient?s reliability is measured by 3 parameters, namely rate of false positive and false...

February 29, 2008

Normal intraocular pressure in an eye with central retinal vein occlusion does not rule out associated glaucoma

Tip of the month

Normal intraocular pressure in an eye with central retinal vein occlusion does not rule out associated glaucoma

The Science behind the Tip Ocular hypertension (OH) and primary open-angle glaucoma (POAG) are strongly associated with (hemi)central retinal vein...

January 31, 2008

Medication compliance can easily be improved

Tip of the month

Medication compliance can easily be improved

The Science behind the Tip Poor medication compliance (i.e. patients not taking their medication as directed) is a major problem in glaucoma care....

December 31, 2007

Poor visit keeping is associated with poor medication compliance

Tip of the month

Poor visit keeping is associated with poor medication compliance

The Science behind the Tip Factors associated with poor medication compliance have been determined for a number of chronic internal disorders that...

November 30, 2007

Heart failure is no contraindication to β-blocker therapy

Tip of the month

Heart failure is no contraindication to β-blocker therapy

The Science behind the Tip Contrary to long-held beliefs, ß-blockers do not aggravate heart failure and are even beneficial in the treatment of the...

October 31, 2007

Diabetes is no manifest risk factor for developing primary open-angle glaucoma

Tip of the month

Diabetes is no manifest risk factor for developing primary open-angle glaucoma

The Science behind the Tip There has been a widely held belief that diabetes increases the risk of developing primary open-angle glaucoma (POAG)....

September 30, 2007

Bilateral acute angle-closure glaucoma may occur after uneventful blepharoplasty

Tip of the month

Bilateral acute angle-closure glaucoma may occur after uneventful blepharoplasty

The Science behind the Tip Bilateral acute angle-closure glaucoma is a possible (potentially blinding) complication after uneventful eyelid...

June 30, 2007

Optic disc size can be quickly assessed at the slit lamp

Tip of the month

Optic disc size can be quickly assessed at the slit lamp

The Science behind the Tip Optic disc size influences the significance of the cup/disc ratio1,2. Disc size can be estimated using a handheld high...

May 31, 2007

Glaucoma and small optic discs: a diagnosis challenge

Tip of the month

Glaucoma and small optic discs: a diagnosis challenge

The Science behind the Tip Diagnosis and follow-up of glaucoma is challenging in eyes with small optic discs (height < 1.2 mm or surface area...

April 30, 2007

Tracking structural abnormalities is more important in early glaucoma than at the end of the disease

Tip of the month

Tracking structural abnormalities is more important in early glaucoma than at the end of the disease

The Science behind the Tip Diagnosing glaucoma and documenting progression at an early stage of the disease is a key thing to successful glaucoma...

March 31, 2007

Target pressure is now an accepted part of standard glaucoma care

Tip of the month

Target pressure is now an accepted part of standard glaucoma care

The Science behind the Tip Target pressure is an estimate of the mean intraocular pressure (IOP) obtained with therapy that is expected to prevent...

December 31, 2006

Early aggressive treatment is indicated in selected glaucoma cases

Tip of the month

Early aggressive treatment is indicated in selected glaucoma cases

The Science behind the Tip In the Early Manifest Glaucoma Trial (EMGT)(1) patients treated had half of the progression risk of control patients....

November 30, 2006