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  • Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    The Science behind the Tip In contrast to underdiagnosis, which has been described in population-based studies as affecting 50% or more of glaucoma...

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    Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    The Science behind the Tip In contrast to underdiagnosis, which has been described in...

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  • Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    PURPOSE: The frequent use of optical coherence tomography increased the detection of peripapillary retinoschisis, which poses challenges in the...

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    Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    PURPOSE: The frequent use of optical coherence tomography increased the detection of...

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  • Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Purpose: To determine whether primary trabeculectomy or medical treatment produces better outcomes in terms of quality of life (QoL), clinical...

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    Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Purpose: To determine whether primary trabeculectomy or medical treatment produces better...

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  • Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway undeniably plays a pivotal role in the pathophysiology...

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    Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Chase the family of primary-open angle glaucoma patients

Tip of the month

Chase the family of primary-open angle glaucoma patients

The Science behind the Tip Various modes of screening for primary open-angle glaucoma (POAG), i.e. different combinations of tonometry and...

November 30, 2008

Intraocular pressure should be monitored after an acute episode of angle-closure

Tip of the month

Intraocular pressure should be monitored after an acute episode of angle-closure

The Science behind the Tip Treatment of acute attacks of angle-closure glaucoma induced by pupillary block is based on medical therapy aiming at...

October 31, 2008

Topical medication may accelerate cataract formation

Tip of the month

Topical medication may accelerate cataract formation

The Science behind the Tip A number of large studies have linked use of topical glaucoma medication with increased risk of nuclear cataract, the...

September 30, 2008

Closing the eyes as an alternative for nasolacrimal duct occlusion

Tip of the month

Closing the eyes as an alternative for nasolacrimal duct occlusion

The Science behind the Tip The Science behind the Tip Manual nasolacrimal occlusion after eye drop instillation is often taught to glaucoma...

June 30, 2008

There is no significant association between use of β-blockers and depression

Tip of the month

There is no significant association between use of β-blockers and depression

The Science behind the Tip The Science behind the Tip The methodological quality of early studies of the association of systemic or topical...

May 31, 2008

Trabeculectomy significantly increases the incidence of cataract formation

Tip of the month

Trabeculectomy significantly increases the incidence of cataract formation

The Science behind the Tip The Science behind the Tip It is widely acknowledged that trabeculectomy (TRAB) accelerates cataract formation. The...

April 30, 2008

Concomitant therapy with Cosopt® and Diamox® is not useful

Tip of the month

Concomitant therapy with Cosopt® and Diamox® is not useful

The Science behind the Tip Although the ß-blocker timolol and the topical carbonic anhydrase inhibitor (CAI) dorzolamide both act by decreased...

March 31, 2008

Rate of false positive answers is the only reliable reliability parameter in computerized perimetry

Tip of the month

Rate of false positive answers is the only reliable reliability parameter in computerized perimetry

The Science behind the Tip In computerized perimetry patient?s reliability is measured by 3 parameters, namely rate of false positive and false...

February 29, 2008

Normal intraocular pressure in an eye with central retinal vein occlusion does not rule out associated glaucoma

Tip of the month

Normal intraocular pressure in an eye with central retinal vein occlusion does not rule out associated glaucoma

The Science behind the Tip Ocular hypertension (OH) and primary open-angle glaucoma (POAG) are strongly associated with (hemi)central retinal vein...

January 31, 2008

Medication compliance can easily be improved

Tip of the month

Medication compliance can easily be improved

The Science behind the Tip Poor medication compliance (i.e. patients not taking their medication as directed) is a major problem in glaucoma care....

December 31, 2007

Poor visit keeping is associated with poor medication compliance

Tip of the month

Poor visit keeping is associated with poor medication compliance

The Science behind the Tip Factors associated with poor medication compliance have been determined for a number of chronic internal disorders that...

November 30, 2007

Heart failure is no contraindication to β-blocker therapy

Tip of the month

Heart failure is no contraindication to β-blocker therapy

The Science behind the Tip Contrary to long-held beliefs, ß-blockers do not aggravate heart failure and are even beneficial in the treatment of the...

October 31, 2007

Diabetes is no manifest risk factor for developing primary open-angle glaucoma

Tip of the month

Diabetes is no manifest risk factor for developing primary open-angle glaucoma

The Science behind the Tip There has been a widely held belief that diabetes increases the risk of developing primary open-angle glaucoma (POAG)....

September 30, 2007

Bilateral acute angle-closure glaucoma may occur after uneventful blepharoplasty

Tip of the month

Bilateral acute angle-closure glaucoma may occur after uneventful blepharoplasty

The Science behind the Tip Bilateral acute angle-closure glaucoma is a possible (potentially blinding) complication after uneventful eyelid...

June 30, 2007

Optic disc size can be quickly assessed at the slit lamp

Tip of the month

Optic disc size can be quickly assessed at the slit lamp

The Science behind the Tip Optic disc size influences the significance of the cup/disc ratio1,2. Disc size can be estimated using a handheld high...

May 31, 2007

Glaucoma and small optic discs: a diagnosis challenge

Tip of the month

Glaucoma and small optic discs: a diagnosis challenge

The Science behind the Tip Diagnosis and follow-up of glaucoma is challenging in eyes with small optic discs (height < 1.2 mm or surface area...

April 30, 2007

Tracking structural abnormalities is more important in early glaucoma than at the end of the disease

Tip of the month

Tracking structural abnormalities is more important in early glaucoma than at the end of the disease

The Science behind the Tip Diagnosing glaucoma and documenting progression at an early stage of the disease is a key thing to successful glaucoma...

March 31, 2007

Target pressure is now an accepted part of standard glaucoma care

Tip of the month

Target pressure is now an accepted part of standard glaucoma care

The Science behind the Tip Target pressure is an estimate of the mean intraocular pressure (IOP) obtained with therapy that is expected to prevent...

December 31, 2006

Early aggressive treatment is indicated in selected glaucoma cases

Tip of the month

Early aggressive treatment is indicated in selected glaucoma cases

The Science behind the Tip In the Early Manifest Glaucoma Trial (EMGT)(1) patients treated had half of the progression risk of control patients....

November 30, 2006

Check intraocular pressure up to several months after intravitreal injection of triamcinolone acetonide

Tip of the month

Check intraocular pressure up to several months after intravitreal injection of triamcinolone acetonide

The Science behind the Tip Intravitreal injection of triamcinolone acetonide (TA) is a relatively novel component of treatment of intraocular...

September 30, 2006

Track structural changes in early disease and functional loss at the end of the disease

Tip of the month

Track structural changes in early disease and functional loss at the end of the disease

The Science behind the Tip Patients with primary open-angle glaucoma can go blind if they already have advanced field loss before they are...

September 30, 2006