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  • Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate their impact on success rates. DESIGN: Systematic...

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    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate...

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  • A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health conditions in retinal images and expediting the...

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    A foundation model for generalizable disease detection from retinal images

    A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health...

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  • Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation compares medical and surgical management...

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    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation...

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  • Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT) has brought attention to rare side effects such as...

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    Beware of acute corneal oedema after SLT in selected patients

    Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT)...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Consider additional 10-2 visual field testing for diagnosing glaucoma, as limiting to 24-2 or 30-2 tests will frequently miss or underestimate paracentral field defects

Tip of the month

Consider additional 10-2 visual field testing for diagnosing glaucoma, as limiting to 24-2 or 30-2 tests will frequently miss or underestimate paracentral field defects

The Science behind the Tip (1,2) It is well-established that damage to macular retinal ganglion cells (RGCs) occurs early in glaucoma (1). Not...

September 30, 2019

When performing a laser peripheral iridotomy (LPI) for primary angle closure the position of the iridotomy in relation to the eyelid should always be considered

Tip of the month

When performing a laser peripheral iridotomy (LPI) for primary angle closure the position of the iridotomy in relation to the eyelid should always be considered

The Science behind the Tip (1,2,3) The incidence of reported dysphotopsias after an LPI varies from 2% to 11% with linear dysphotopsia and...

July 31, 2019

Avoid the use of monocular prostaglandin analogue medication

Tip of the month

Avoid the use of monocular prostaglandin analogue medication

The Science behind the Tip Where glaucoma predominantly affects one eye, monocular therapy may be used. Prostaglandin analogues are widely used as...

July 31, 2019

A glaucoma patient who progresses despite presumed good adherence might be using inadequate or insufficient technique when applying the anti-glaucomatous eye drops

Tip of the month

A glaucoma patient who progresses despite presumed good adherence might be using inadequate or insufficient technique when applying the anti-glaucomatous eye drops

The Science behind the Tip It is well known that if poor technique is used when a drop is applied to the eye it does not reach its target. This can...

June 30, 2019

Selective Laser Trabeculoplasty (SLT) can be considered as the first treatment for newly diagnosed patients with ocular hypertension and mild to moderate primary open angle glaucoma

Tip of the month

Selective Laser Trabeculoplasty (SLT) can be considered as the first treatment for newly diagnosed patients with ocular hypertension and mild to moderate primary open angle glaucoma

The Science behind the Tip The LiGHT trial compared two treatment pathways for treatment naïve ocular hypertension and mild to moderate glaucoma....

May 31, 2019

Ocular coherence tomography (OCT) should be used cautiously in the context of uveitic glaucoma

Tip of the month

Ocular coherence tomography (OCT) should be used cautiously in the context of uveitic glaucoma

The Science behind the Tip Patients with uveitis have a heightened risk of developing secondary glaucoma. Ocular Coherence Tomography (OCT) imaging...

March 31, 2019

Depression may follow a diagnosis of chronic glaucoma, but depressive symptoms are less likely to be present one year later

Tip of the month

Depression may follow a diagnosis of chronic glaucoma, but depressive symptoms are less likely to be present one year later

The Science behind the Tip It is common for a newly-diagnosed patient with glaucoma to experience symptoms of depression (1,2). Patients who are...

March 01, 2019

Early bleb revision usually results in successful resolution of hypotony maculopathy after trabeculectomy with mitomycin C

Tip of the month

Early bleb revision usually results in successful resolution of hypotony maculopathy after trabeculectomy with mitomycin C

The Science behind the Tip Hypotony maculopathy is characterized by painless loss of vision usually more than three months after glaucoma...

January 31, 2019

Children using topical corticosteroids for the treatment of allergic conjunctivitis must have their intraocular pressure regularly checked

Tip of the month

Children using topical corticosteroids for the treatment of allergic conjunctivitis must have their intraocular pressure regularly checked

The Science behind the Tip 30-40% of the population respond to topical steroids by increasing their IOP (1). A steroid response is commonly found...

December 31, 2018

The results of trabeculectomy with mitomycin C are significantly improved in children with glaucoma secondary to juvenile idiopathic arthritis if they are on immune-modulatory treatment

Tip of the month

The results of trabeculectomy with mitomycin C are significantly improved in children with glaucoma secondary to juvenile idiopathic arthritis if they are on immune-modulatory treatment

The Science behind the Tip Juvenile idiopathic arthritis (JIA) is the most common systemic disease associated with childhood anterior uveitis....

November 30, 2018

Microperimetry may be a more sensitive method of detecting a small glaucomatous defect close to fixation, than standard automated perimetry and OCT analysis of the retinal nerve fibre layer (RNFL)

Tip of the month

Microperimetry may be a more sensitive method of detecting a small glaucomatous defect close to fixation, than standard automated perimetry and OCT analysis of the retinal nerve fibre layer (RNFL)

The Science behind the Tip Microperimetry is a form of fundus-tracking perimetry that can detect reduced retinal sensitivity close to fixation more...

October 31, 2018

A glaucoma drainage device may be more effective than trabeculectomy in lowering IOP after keratoplasty, but is more likely to result in graft failure

Tip of the month

A glaucoma drainage device may be more effective than trabeculectomy in lowering IOP after keratoplasty, but is more likely to result in graft failure

The Science behind the Tip A well-controlled intraocular pressure (IOP) after penetrating keratoplasty (PK) is essential for graft survival and to...

September 30, 2018

When determining a therapeutic approach to a patient with glaucoma, the life expectancy of the patient needs to be considered

Tip of the month

When determining a therapeutic approach to a patient with glaucoma, the life expectancy of the patient needs to be considered

The Science behind the Tip Patients who present with early glaucoma who have a short life expectancy are unlikely to go blind from glaucoma in...

June 30, 2018

The insertion of a punctal plug improves ocular comfort and results in a modest reduction of IOP in patients with glaucoma who are using topical medication

Tip of the month

The insertion of a punctal plug improves ocular comfort and results in a modest reduction of IOP in patients with glaucoma who are using topical medication

The Science behind the Tip Patients with ocular hypertension and chronic glaucoma have a higher prevalence of ocular surface disease (OSD) than...

May 31, 2018

In a patient with pigment dispersion syndrome, the most significant ocular risk factor for conversion to glaucoma is an IOP above 21mmHg on presentation

Tip of the month

In a patient with pigment dispersion syndrome, the most significant ocular risk factor for conversion to glaucoma is an IOP above 21mmHg on presentation

The Science behind the Tip Pigment dispersion syndrome tends to occur in young myopic white men. There are genetic factors that underly the risk...

April 30, 2018

Validated prediction models are helpful to determine the risk of an individual with ocular hypertension developing chronic glaucoma

Tip of the month

Validated prediction models are helpful to determine the risk of an individual with ocular hypertension developing chronic glaucoma

The Science behind the Tip Raised intraocular pressure (IOP) is an important risk factor for the development of glaucoma and can be modified with...

March 31, 2018

Measuring the intraocular pressure (IOP) not only in sitting, but also in supine position, may help to identify the 24-hour IOP characteristics of your glaucoma patient

Tip of the month

Measuring the intraocular pressure (IOP) not only in sitting, but also in supine position, may help to identify the 24-hour IOP characteristics of your glaucoma patient

The Science behind the Tip It is well known that each patient has an individual circadian IOP pattern. Studies have shown that up to two thirds of...

February 28, 2018

Treatment of ischaemic central retinal vein occlusion with prophylactic anti-VEGF injections reduces the risk of neovascular glaucoma, but careful long-term monitoring for ocular new vessels remains essential

Tip of the month

Treatment of ischaemic central retinal vein occlusion with prophylactic anti-VEGF injections reduces the risk of neovascular glaucoma, but careful long-term monitoring for ocular new vessels remains essential

The Science behind the Tip Approximately 20% of central retinal vein occlusions (CRVO) are ischaemic and of those, 45% develop neovascular...

January 31, 2018

OCT measurement of the retinal nerve fibre layer is useful for detecting progression in early glaucoma

Tip of the month

OCT measurement of the retinal nerve fibre layer is useful for detecting progression in early glaucoma

The Science behind the Tip Both visual field testing and optical coherence tomography (OCT) measurements can be used to detect glaucomatous...

December 31, 2017

Bleb encapsulation after trabeculectomy can be successfully treated by using aqueous suppressant treatment for a short period

Tip of the month

Bleb encapsulation after trabeculectomy can be successfully treated by using aqueous suppressant treatment for a short period

The Science behind the Tip Bleb encapsulation may occur 2 to 6 weeks after trabeculectomy, when an elevated, tense, dome-shaped bleb develops with...

November 30, 2017

A patient who presents with raised intraocular pressure or glaucoma and distended episcleral veins in one eye needs to be investigated for a spontaneous carotid – cavernous fistula

Tip of the month

A patient who presents with raised intraocular pressure or glaucoma and distended episcleral veins in one eye needs to be investigated for a spontaneous carotid – cavernous fistula

The Science behind the Tip A carotid – cavernous sinus fistula is an abnormal vascular communication between the carotid artery system and the...

October 31, 2017

Glaucoma associated with congenital aniridia is difficult to treat, but tube-shunt drainage devices offer the best results

Tip of the month

Glaucoma associated with congenital aniridia is difficult to treat, but tube-shunt drainage devices offer the best results

The Science behind the Tip Congenital aniridia is a rare bilateral developmental disorder which is inherited in an autosomal dominant fashion in...

September 30, 2017

In a young patient with acute congestive angle closure or recurrent angle closure in the presence of a patent laser iridotomy, the underlying cause is usually plateau iris configuration

Tip of the month

In a young patient with acute congestive angle closure or recurrent angle closure in the presence of a patent laser iridotomy, the underlying cause is usually plateau iris configuration

The Science behind the Tip Plateau iris configuration is characterised by a closed anterior chamber angle in association with a flat iris plane and...

July 31, 2017

The chronic use of prostaglandin analogues may lead to a modest underestimation of IOP when measured by Goldmann applanation tonometry

Tip of the month

The chronic use of prostaglandin analogues may lead to a modest underestimation of IOP when measured by Goldmann applanation tonometry

The Science behind the Tip Corneal hysteresis is a biomechanical property of the cornea relating to its elasticity. The measurement of corneal...

June 30, 2017

In a patient with glaucoma who has unexplained hair loss, stop topical beta-blocker treatment

Tip of the month

In a patient with glaucoma who has unexplained hair loss, stop topical beta-blocker treatment

The Science behind the Tip Beta adrenergic receptor blocking eye drops are often used to reduce the intraocular pressure. Because of absorption...

May 31, 2017