• Childhood Glaucoma

    SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma is a rare but severe ocular condition that can...

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    Childhood Glaucoma

    Childhood Glaucoma

    SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...

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  • Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing it too early can lead to postoperative hypotony and...

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    Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...

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  • Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional loss in glaucoma; (2) To evaluate the importance...

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    Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...

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  • Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Purpose: A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients...

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    Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Purpose: A previously developed machine-learning approach with Kalman filtering technology...

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  • Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned people. This sociological concept is a result of...

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    Fatal beauty: which cosmetics are your glaucoma patients using?

    Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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Delaying Treatment of Ocular Hypertension: the Ocular Hypertension Treatment Study

Clinical paper of the month

Delaying Treatment of Ocular Hypertension: the Ocular Hypertension Treatment Study

Author(s): Michael A. Kass, MD; Mae O. Gordon, PhD; Feng Gao, PhD; Dale K. Heuer, MD; Eve J. Higginbotham, MD; Chris A. Johnson, PhD; John K....

May 31, 2010

Neuroprotective Effects of Intravitreal Mesenchymal Stem Cell Transplantation in Experimental Glaucoma

Experimental Paper of the Month

Neuroprotective Effects of Intravitreal Mesenchymal Stem Cell Transplantation in Experimental Glaucoma

Author(s): Thomas V. Johnson(1,2,3) Natalie D. Bull(1,2) David P. Hunt(1), Nephtali Marina(1), Stanislav I. Tomarev(3), Keith R. Martin(1) Centre...

May 31, 2010

Disc Haemorrhages

Tip of the month

Disc Haemorrhages

The Science behind the Tip Although described most commonly in normal tension glaucoma, optic disc haemorrhages may occur in all forms of glaucoma....

April 30, 2010

When should neuroradiological imaging be undertaken in patients with normal tension glaucoma?

Tip of the month

When should neuroradiological imaging be undertaken in patients with normal tension glaucoma?

The Science behind the Tip Clinicians must remain vigilant to detect intracranial pathology in patients with normal tension glaucoma. Most patients...

March 31, 2010

Simvastatin and Disease Stabilization in Normal Tension Glaucoma: A Cohort Study.

Clinical paper of the month

Simvastatin and Disease Stabilization in Normal Tension Glaucoma: A Cohort Study.

Author(s): Leung DY, Li FC, Kwong YY, Tham CC, Chi SC, Lam DS. Department of Ophthalmology and Visual Sciences, The Chinese University of Hong...

March 31, 2010

Episcleral Venous Pressure Responses to Topical Nitroprusside and N-Nitro-L-arginine Methyl Ester.

Experimental Paper of the Month

Episcleral Venous Pressure Responses to Topical Nitroprusside and N-Nitro-L-arginine Methyl Ester.

Author(s): Zamora DO, Kiel JW. Department of Ophthalmology, University of Texas Health Science Center, San Antonio, Texas. PURPOSE: To determine...

March 31, 2010

Cerebrospinal Fluid Pressure in Glaucoma A Prospective Study.

Clinical paper of the month

Cerebrospinal Fluid Pressure in Glaucoma A Prospective Study.

Author(s): Ren R, Jonas JB, Tian G, Zhen Y, Ma K, Li S, Wang H, Li B, Zhang X, Wang N Beijing Institute of Ophthalmology, Beijing Tongren Eye...

February 28, 2010

Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation.

Experimental Paper of the Month

Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation.

Author(s): Tezel G, Yang X, Luo C, Cai J, Kain AD, Powell DW, Kuehn MH, Pierce WM Department of Ophthalmology and Visual Sciences, University of...

February 28, 2010

Prediction of glaucomatous visual field loss by extrapolation of linear trends

Clinical paper of the month

Prediction of glaucomatous visual field loss by extrapolation of linear trends

Author(s): Bengtsson B, Patella VM, Heijl A Departments of Clinical Sciences and Ophthalmology, Lund University, Malmö University Hospital,...

January 31, 2010

Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration

Experimental Paper of the Month

Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration

Author(s): Salinas-Navarro M, Alarcón-Martínez L, Valiente-Soriano FJ, Jiménez-López M, Mayor-Torroglosa S, Avilés-Trigueros M, Villegas-Pérez MP,...

January 31, 2010

Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study

Clinical paper of the month

Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study

Author(s): Topouzis F, Harris A, Wilson MR, Koskosas A, Founti P, Yu F, Anastasopoulos E, Pappas T, Coleman AL Department of Ophthalmology, School...

November 30, 2009

Complex antibody profile changes in an experimental autoimmune glaucoma animal model

Clinical paper of the month

Complex antibody profile changes in an experimental autoimmune glaucoma animal model

Author(s): Joachim SC, Grus FH, Kraft D, White-Farrar K, Barnes G, Barbeck M, Ghanaati S, Cao S, Li B, Wax MB Experimental Ophthalmology,...

October 31, 2009

Glaucoma medications may harm the foetus and neonate

Tip of the month

Glaucoma medications may harm the foetus and neonate

The Science behind the Tip Human data on adverse effects of glaucoma medications during pregnancy and lactation are sparse because the coincidence...

May 31, 2009

Intraocular pressure is overestimated in eyes with a thick cornea

Tip of the month

Intraocular pressure is overestimated in eyes with a thick cornea

The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of Goldmann applanation tonometry (GAT)(1). The...

April 30, 2009

A thin cornea is a risk factor for primary open-angle glaucoma

Tip of the month

A thin cornea is a risk factor for primary open-angle glaucoma

The Science behind the Tip Central corneal thickness (CCT) varies among individuals, the average CCT in the general population being approximately...

March 31, 2009

Intraocular pressure is underestimated in eyes with a thin cornea

Tip of the month

Intraocular pressure is underestimated in eyes with a thin cornea

The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of applanation tonometry techniques such as...

February 28, 2009

Visual field defects are filled-in by the brain

Tip of the month

Visual field defects are filled-in by the brain

The Science behind the Tip Contrary to long held beliefs, cortical maps in the brain are not rigid. Extensive reorganization (i.e. brain remapping)...

January 31, 2009

Pseudoexfoliation glaucoma has a strong genetic component

Tip of the month

Pseudoexfoliation glaucoma has a strong genetic component

Publishing date: December 2008 The Science behind the Tip Pseudoexfoliation or exfoliation syndrome (PEX) is the most common identifiable condition...

December 31, 2008

Chase the family of primary-open angle glaucoma patients

Tip of the month

Chase the family of primary-open angle glaucoma patients

The Science behind the Tip Various modes of screening for primary open-angle glaucoma (POAG), i.e. different combinations of tonometry and...

November 30, 2008

Intraocular pressure should be monitored after an acute episode of angle-closure

Tip of the month

Intraocular pressure should be monitored after an acute episode of angle-closure

The Science behind the Tip Treatment of acute attacks of angle-closure glaucoma induced by pupillary block is based on medical therapy aiming at...

October 31, 2008

Topical medication may accelerate cataract formation

Tip of the month

Topical medication may accelerate cataract formation

The Science behind the Tip A number of large studies have linked use of topical glaucoma medication with increased risk of nuclear cataract, the...

September 30, 2008

Closing the eyes as an alternative for nasolacrimal duct occlusion

Tip of the month

Closing the eyes as an alternative for nasolacrimal duct occlusion

The Science behind the Tip The Science behind the Tip Manual nasolacrimal occlusion after eye drop instillation is often taught to glaucoma...

June 30, 2008

There is no significant association between use of β-blockers and depression

Tip of the month

There is no significant association between use of β-blockers and depression

The Science behind the Tip The Science behind the Tip The methodological quality of early studies of the association of systemic or topical...

May 31, 2008

Trabeculectomy significantly increases the incidence of cataract formation

Tip of the month

Trabeculectomy significantly increases the incidence of cataract formation

The Science behind the Tip The Science behind the Tip It is widely acknowledged that trabeculectomy (TRAB) accelerates cataract formation. The...

April 30, 2008

Concomitant therapy with Cosopt® and Diamox® is not useful

Tip of the month

Concomitant therapy with Cosopt® and Diamox® is not useful

The Science behind the Tip Although the ß-blocker timolol and the topical carbonic anhydrase inhibitor (CAI) dorzolamide both act by decreased...

March 31, 2008