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Tip: Not every peripapillary hemorrhage is a sign for glaucoma
The Science behind the Tip Most of the time, disc hemorrhages in patients with glaucoma are...
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The Factors Affecting the Stability of IOP Homeostasis
Purpose: Shear-induced nitric oxide (NO) production by Schlemm's canal (SC) endothelial cells...
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Short-term Detection of Fast Progressors in Glaucoma: The Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study
Purpose: To evaluate the performance of an intensive, clustered testing approach in identifying...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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Neuroprotection in Glaucoma: Towards Clinical Trials and Precision Medicine
Author(s): Khatib TZ (1,2,3), Martin KR (1,2,4,5,6,7) 1 John Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of...
November 30, 2019
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Glaucoma following childhood cataract surgery
Pearls Manager: Andrew Tatham Secondary glaucoma is a frequent serious complication after cataract surgery in early infancy. The incidence may...
November 30, 2019
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Consider using a topical NSAID, or steroid, post SLT laser
The Science behind the Tip There is widespread variation in post laser treatment regimes. In a recent randomized, double-masked, multi-center...
October 31, 2019
Exogenous influences on intraocular pressure
Author(s): Kim YW (1), Park KH (2) 1 Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea. 2 Ophthalmology, Seoul National...
October 31, 2019
Cholinergic nervous system and glaucoma: From basic science to clinical applications
Author(s): Faiq MA (1), Wollstein G (1), Schuman JS (1), Chan KC (2) 1 Department of Ophthalmology, New York University (NYU) School of Medicine,...
October 31, 2019
Ocular Blood Flow SIG
SIG Corner Editor: João Barbosa Breda Chair: Leopold Schmetterer Co-chair: Luis Abegão Pinto 1. Ongoing projects The Ocular Blood Flow SIG and its...
October 24, 2019
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Gonioscopy is essential for evaluating patients with a suspected or confirmed diagnosis of glaucoma
Pearls Manager: Andrew Tatham The corneal wedge method is helpful for identifying Schwalbe’s line, a collagen condensation of the Descemet’s...
October 22, 2019
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Consider additional 10-2 visual field testing for diagnosing glaucoma, as limiting to 24-2 or 30-2 tests will frequently miss or underestimate paracentral field defects
The Science behind the Tip (1,2) It is well-established that damage to macular retinal ganglion cells (RGCs) occurs early in glaucoma (1). Not...
September 30, 2019
Predictors of Neovascular Glaucoma in Central Retinal Vein Occlusion
Author(s): Rong AJ (1), Swaminathan SS (2), Vanner EA (3), Parrish RK 2nd (3) 1 Department of Ophthalmology, Bascom Palmer Eye Institute,...
September 30, 2019
microRNA dysregulation in neurodegenerative diseases: A systematic review
Author(s): Juźwik CA (1), Sage-Drake S (2), Zhang Y (3), Paradis-Isler N (4), Sylvester A (5), Amar-Zifkin A (6), Douglas C (7), Morquette B (8),...
September 30, 2019
Genetic Epidemiology SIG
SIG Corner Editor: João Barbosa Breda Chair: Ananth Viswanathan Co-chair: Fotis Topouzis NGP Co-chair: Anthony Khawaja NGP Co-chair: Panayiota...
September 30, 2019
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Clinical examination of the optic nerve head
Pearls Manager: Andrew Tatham Cup/disc ratio (CDR) depends on optic disc size. A large CDR in an eye with a normal large disc may be erroneously...
September 30, 2019
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When performing a laser peripheral iridotomy (LPI) for primary angle closure the position of the iridotomy in relation to the eyelid should always be considered
The Science behind the Tip (1,2,3) The incidence of reported dysphotopsias after an LPI varies from 2% to 11% with linear dysphotopsia and...
July 31, 2019
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Avoid the use of monocular prostaglandin analogue medication
The Science behind the Tip Where glaucoma predominantly affects one eye, monocular therapy may be used. Prostaglandin analogues are widely used as...
July 31, 2019
Effect of trabeculectomy on corneal endothelial cell loss
Author(s): Hirooka K (1), Nitta E (2), Ukegawa K (2), Sato S (2), Kiuchi Y (3) 1 Ophthalmology and Visual Science, Hiroshima University, Hiroshima,...
July 31, 2019
Potential role of P2X7 receptor in neurodegenerative processes in a murine model of glaucoma
Author(s): Pérez de Lara MJ (1), Avilés-Trigueros M (2), Guzmán-Aránguez A (1), Valiente-Soriano FJ (2), de la Villa P (3), Vidal-Sanz M (4),...
July 31, 2019
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Adherence to glaucoma medication
Pearls Manager: Andrew Tatham Obstacles to glaucoma medication adherence include; 1) situational and environmental factors such as major life...
July 30, 2019
Surgery SIG
SIG Corner Editor: João Barbosa Breda Chair: Julián Garcia-Feijoo Co-chair: Keith Barton 1. Ongoing projects SURGERY REGISTRY The European Glaucoma...
July 26, 2019
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Prevalence of Treatment With Glaucoma Medication in Scotland, 2010-2017
Author(s): Alan P Rotchford (1), John Hughes (2), Pankaj Kumar Agarwal (3), Andrew J Tatham (3) Ophthalmology, Tennent Institute of Ophthalmology,...
July 20, 2019
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A glaucoma patient who progresses despite presumed good adherence might be using inadequate or insufficient technique when applying the anti-glaucomatous eye drops
The Science behind the Tip It is well known that if poor technique is used when a drop is applied to the eye it does not reach its target. This can...
June 30, 2019
Risk factors for disease progression in low-teens normal-tension glaucoma
Author(s): Baek SU (1,2), Ha A (3,4), Kim DW (5,6), Jeoung JW (3,4), Park KH (3,4), Kim YK (7,4) 1 Department of Ophthalmology, Hallym University...
June 30, 2019
Impact of Posterior Sclera on Glaucoma Progression in Treated Myopic Normal-Tension Glaucoma Using Reconstructed Optical Coherence Tomographic Images
Author(s): Kim YC (1), Koo YH (2), Jung KI (3), Park CK (3) 1 Department of Ophthalmology, College of Medicine, Incheon St. Mary's Hospital, The...
June 30, 2019
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Glaucoma due to corticosteroids
Pearls Manager: Andrew Tatham Topical, intravitreal or systemic corticosteroids can induce acute or chronic intraocular pressure elevation. Risk...
June 30, 2019
Neuroprotection SIG
SIG Corner Editor: João Barbosa Breda Chair: Francesca Cordeiro Co-chair: Miriam Kolko 1. Goals of the SIG SIG neuroprotection forms the basis of...
June 27, 2019
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Selective Laser Trabeculoplasty (SLT) can be considered as the first treatment for newly diagnosed patients with ocular hypertension and mild to moderate primary open angle glaucoma
The Science behind the Tip The LiGHT trial compared two treatment pathways for treatment naïve ocular hypertension and mild to moderate glaucoma....
May 31, 2019