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  • Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    The Science behind the Tip In contrast to underdiagnosis, which has been described in population-based studies as affecting 50% or more of glaucoma...

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    Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    Balancing Glaucoma Care: Tackling Overdiagnosis and Overtreatment to Preserve Patient Quality of Life

    The Science behind the Tip In contrast to underdiagnosis, which has been described in...

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  • Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    PURPOSE: The frequent use of optical coherence tomography increased the detection of peripapillary retinoschisis, which poses challenges in the...

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    Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    Peripapillary Retinoschisis in Glaucoma: A Systematic Review

    PURPOSE: The frequent use of optical coherence tomography increased the detection of...

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  • Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Purpose: To determine whether primary trabeculectomy or medical treatment produces better outcomes in terms of quality of life (QoL), clinical...

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    Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    Purpose: To determine whether primary trabeculectomy or medical treatment produces better...

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  • Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway undeniably plays a pivotal role in the pathophysiology...

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    Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

    Purpose: The Rho-associated protein kinase and myosin light chain kinase (ROCK/MYLK) pathway...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Surgery SIG

SIG Corner

Surgery SIG

SIG Corner Editor: João Barbosa Breda Chair: Julián Garcia-Feijoo Co-chair: Keith Barton 1. Ongoing projects SURGERY REGISTRY The European Glaucoma...

July 26, 2019

Prevalence of Treatment With Glaucoma Medication in Scotland, 2010-2017

NGP Paper

Prevalence of Treatment With Glaucoma Medication in Scotland, 2010-2017

Author(s): Alan P Rotchford (1), John Hughes (2), Pankaj Kumar Agarwal (3), Andrew J Tatham (3) Ophthalmology, Tennent Institute of Ophthalmology,...

July 20, 2019

A glaucoma patient who progresses despite presumed good adherence might be using inadequate or insufficient technique when applying the anti-glaucomatous eye drops

Tip of the month

A glaucoma patient who progresses despite presumed good adherence might be using inadequate or insufficient technique when applying the anti-glaucomatous eye drops

The Science behind the Tip It is well known that if poor technique is used when a drop is applied to the eye it does not reach its target. This can...

June 30, 2019

Risk factors for disease progression in low-teens normal-tension glaucoma

Clinical paper of the month

Risk factors for disease progression in low-teens normal-tension glaucoma

Author(s): Baek SU (1,2), Ha A (3,4), Kim DW (5,6), Jeoung JW (3,4), Park KH (3,4), Kim YK (7,4) 1 Department of Ophthalmology, Hallym University...

June 30, 2019

Impact of Posterior Sclera on Glaucoma Progression in Treated Myopic Normal-Tension Glaucoma Using Reconstructed Optical Coherence Tomographic Images

Experimental Paper of the Month

Impact of Posterior Sclera on Glaucoma Progression in Treated Myopic Normal-Tension Glaucoma Using Reconstructed Optical Coherence Tomographic Images

Author(s): Kim YC (1), Koo YH (2), Jung KI (3), Park CK (3) 1 Department of Ophthalmology, College of Medicine, Incheon St. Mary's Hospital, The...

June 30, 2019

Glaucoma due to corticosteroids

Pearl

Glaucoma due to corticosteroids

Pearls Manager: Andrew Tatham Topical, intravitreal or systemic corticosteroids can induce acute or chronic intraocular pressure elevation. Risk...

June 30, 2019

Neuroprotection SIG

SIG Corner

Neuroprotection SIG

SIG Corner Editor: João Barbosa Breda Chair: Francesca Cordeiro Co-chair: Miriam Kolko 1. Goals of the SIG SIG neuroprotection forms the basis of...

June 27, 2019

Selective Laser Trabeculoplasty (SLT) can be considered as the first treatment for newly diagnosed patients with ocular hypertension and mild to moderate primary open angle glaucoma

Tip of the month

Selective Laser Trabeculoplasty (SLT) can be considered as the first treatment for newly diagnosed patients with ocular hypertension and mild to moderate primary open angle glaucoma

The Science behind the Tip The LiGHT trial compared two treatment pathways for treatment naïve ocular hypertension and mild to moderate glaucoma....

May 31, 2019

Exogenous influences on intraocular pressure

Clinical paper of the month

Exogenous influences on intraocular pressure

Author(s): Kim YW (1), Park KH (2) 1 Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea. 2 Ophthalmology, Seoul National...

May 31, 2019

Rapamycin Removes Damaged Mitochondria and Protects Human Trabecular Meshwork (TM-1) Cells from Chronic Oxidative Stress

Experimental Paper of the Month

Rapamycin Removes Damaged Mitochondria and Protects Human Trabecular Meshwork (TM-1) Cells from Chronic Oxidative Stress

Author(s): He JN (1,2), Zhang SD (3), Qu Y (2), Wang HL (2), Tham CC (1), Pang CP (1), Chu WK (4) 1 Department of Ophthalmology and Visual...

May 31, 2019

Angle Closure SIG

SIG Corner

Angle Closure SIG

SIG Corner Editor: João Barbosa Breda Chair: John Thygesen Co-chair: Gus Gazzard 1. Goals and Activities of the SIG The Angle Closure SIG promotes...

May 30, 2019

Glaucoma and intraocular bleeding

Pearl

Glaucoma and intraocular bleeding

Pearls Manager: Andrew Tatham Either acute bleeding in the anterior chamber or long standing blood in the vitreous of any source can cause IOP...

May 30, 2019

Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial

Clinical paper of the month

Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial

Author(s): Gazzard G (1), Konstantakopoulou E (2), Garway-Heath D (2), Garg A (2), Vickerstaff V (3), Hunter R (4), Ambler G (5), Bunce C (6),...

April 30, 2019

Border Tissue Morphology is Spatially Associated with Focal Lamina Cribrosa Defect and Deep-Layer Microvasculature Dropout in Open-Angle Glaucoma

Experimental Paper of the Month

Border Tissue Morphology is Spatially Associated with Focal Lamina Cribrosa Defect and Deep-Layer Microvasculature Dropout in Open-Angle Glaucoma

Author(s): Han JC (1), Choi JH (1), Park DY (1), Lee EJ (1), Kee C (2) 1 Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan...

April 30, 2019

Management of glaucoma during pregnancy

Pearl

Management of glaucoma during pregnancy

Pearls Manager: Andrew Tatham Women with glaucoma of child bearing age should be informed about the possible need to modify treatment during...

April 30, 2019

Imaging SIG

SIG Corner

Imaging SIG

SIG Corner Editor: João Barbosa Breda Chair: Hans LemijCo-chair: David Garway-Heath 1. Goals and Activities of the SIG The Imaging SIG’s main...

April 01, 2019

Ocular coherence tomography (OCT) should be used cautiously in the context of uveitic glaucoma

Tip of the month

Ocular coherence tomography (OCT) should be used cautiously in the context of uveitic glaucoma

The Science behind the Tip Patients with uveitis have a heightened risk of developing secondary glaucoma. Ocular Coherence Tomography (OCT) imaging...

March 31, 2019

Visual Crowding in Glaucoma

Clinical paper of the month

Visual Crowding in Glaucoma

Author(s): Ogata NG (1), Boer ER (2), Daga FB (1), Jammal AA (1), Stringham JM (1), Medeiros FA (1) 1 Duke Eye Center, Department of Ophthalmology,...

March 31, 2019

Artificial intelligence and deep learning in ophthalmology

Experimental Paper of the Month

Artificial intelligence and deep learning in ophthalmology

Author(s): Ting DSW (1), Pasquale LR (2), Peng L (3), Campbell JP (4), Lee AY (5), Raman R (6), Tan GSW (7), Schmetterer L (7,8,9,10), Keane PA...

March 31, 2019

Pigmentary glaucoma

Pearl

Pigmentary glaucoma

Pearls Manager: Andrew Tatham Pigmentary glaucoma represents 1 to 1.5% of all glaucoma cases. It is more common in Caucasian myopic men and is...

March 30, 2019

Depression may follow a diagnosis of chronic glaucoma, but depressive symptoms are less likely to be present one year later

Tip of the month

Depression may follow a diagnosis of chronic glaucoma, but depressive symptoms are less likely to be present one year later

The Science behind the Tip It is common for a newly-diagnosed patient with glaucoma to experience symptoms of depression (1,2). Patients who are...

March 01, 2019

The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Inter-eye Comparison Study

Clinical paper of the month

The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Inter-eye Comparison Study

Author(s): Choi JH (1), Han JC, Kee C 1 Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul,...

February 28, 2019

Identification of Candidate miRNA Biomarkers for Glaucoma

Experimental Paper of the Month

Identification of Candidate miRNA Biomarkers for Glaucoma

Author(s): Hindle AG1, Thoonen R2, Jasien JV (3), Grange RMH (1), Amin K (4), Wise J (4), Ozaki M (5), Ritch R (3), Malhotra R (2), Buys ES (1) 1...

February 28, 2019

Care Delivery SIG

SIG Corner

Care Delivery SIG

SIG Corner Editor: João Barbosa Breda Chair: Anton B. Hommer Co-chair: Gabor Holló Update on ongoing projects The goal of this SIG is to get a...

February 28, 2019

How to perform Goldmann applanation tonometry in patients with significant regular corneal astigmatism

Pearl

How to perform Goldmann applanation tonometry in patients with significant regular corneal astigmatism

Pearls Manager: Andrew Tatham When performing Goldmann applanation tonometry in patients with significant regular corneal astigmatism (>3...

February 20, 2019