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Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization
Purpose: Glaucoma is the primary cause of permanent vision loss worldwide. However, the...
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Quality of Life and Primary Open-Angle Glaucoma in the Ocular Hypertension Treatment Study
Importance: If preperimetric glaucoma reduces patient-reported vision-related quality of life...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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Glaucoma medications may harm the foetus and neonate
The Science behind the Tip Human data on adverse effects of glaucoma medications during pregnancy and lactation are sparse because the coincidence...
May 31, 2009
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Intraocular pressure is overestimated in eyes with a thick cornea
The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of Goldmann applanation tonometry (GAT)(1). The...
April 30, 2009
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A thin cornea is a risk factor for primary open-angle glaucoma
The Science behind the Tip Central corneal thickness (CCT) varies among individuals, the average CCT in the general population being approximately...
March 31, 2009
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Intraocular pressure is underestimated in eyes with a thin cornea
The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of applanation tonometry techniques such as...
February 28, 2009
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Visual field defects are filled-in by the brain
The Science behind the Tip Contrary to long held beliefs, cortical maps in the brain are not rigid. Extensive reorganization (i.e. brain remapping)...
January 31, 2009
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Pseudoexfoliation glaucoma has a strong genetic component
Publishing date: December 2008 The Science behind the Tip Pseudoexfoliation or exfoliation syndrome (PEX) is the most common identifiable condition...
December 31, 2008
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Chase the family of primary-open angle glaucoma patients
The Science behind the Tip Various modes of screening for primary open-angle glaucoma (POAG), i.e. different combinations of tonometry and...
November 30, 2008
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Intraocular pressure should be monitored after an acute episode of angle-closure
The Science behind the Tip Treatment of acute attacks of angle-closure glaucoma induced by pupillary block is based on medical therapy aiming at...
October 31, 2008
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Topical medication may accelerate cataract formation
The Science behind the Tip A number of large studies have linked use of topical glaucoma medication with increased risk of nuclear cataract, the...
September 30, 2008
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Closing the eyes as an alternative for nasolacrimal duct occlusion
The Science behind the Tip The Science behind the Tip Manual nasolacrimal occlusion after eye drop instillation is often taught to glaucoma...
June 30, 2008
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There is no significant association between use of β-blockers and depression
The Science behind the Tip The Science behind the Tip The methodological quality of early studies of the association of systemic or topical...
May 31, 2008
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Trabeculectomy significantly increases the incidence of cataract formation
The Science behind the Tip The Science behind the Tip It is widely acknowledged that trabeculectomy (TRAB) accelerates cataract formation. The...
April 30, 2008
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Concomitant therapy with Cosopt® and Diamox® is not useful
The Science behind the Tip Although the ß-blocker timolol and the topical carbonic anhydrase inhibitor (CAI) dorzolamide both act by decreased...
March 31, 2008
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Rate of false positive answers is the only reliable reliability parameter in computerized perimetry
The Science behind the Tip In computerized perimetry patient?s reliability is measured by 3 parameters, namely rate of false positive and false...
February 29, 2008
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Normal intraocular pressure in an eye with central retinal vein occlusion does not rule out associated glaucoma
The Science behind the Tip Ocular hypertension (OH) and primary open-angle glaucoma (POAG) are strongly associated with (hemi)central retinal vein...
January 31, 2008
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Medication compliance can easily be improved
The Science behind the Tip Poor medication compliance (i.e. patients not taking their medication as directed) is a major problem in glaucoma care....
December 31, 2007
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Poor visit keeping is associated with poor medication compliance
The Science behind the Tip Factors associated with poor medication compliance have been determined for a number of chronic internal disorders that...
November 30, 2007
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Heart failure is no contraindication to β-blocker therapy
The Science behind the Tip Contrary to long-held beliefs, ß-blockers do not aggravate heart failure and are even beneficial in the treatment of the...
October 31, 2007
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Diabetes is no manifest risk factor for developing primary open-angle glaucoma
The Science behind the Tip There has been a widely held belief that diabetes increases the risk of developing primary open-angle glaucoma (POAG)....
September 30, 2007
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Bilateral acute angle-closure glaucoma may occur after uneventful blepharoplasty
The Science behind the Tip Bilateral acute angle-closure glaucoma is a possible (potentially blinding) complication after uneventful eyelid...
June 30, 2007
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Optic disc size can be quickly assessed at the slit lamp
The Science behind the Tip Optic disc size influences the significance of the cup/disc ratio1,2. Disc size can be estimated using a handheld high...
May 31, 2007
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Glaucoma and small optic discs: a diagnosis challenge
The Science behind the Tip Diagnosis and follow-up of glaucoma is challenging in eyes with small optic discs (height < 1.2 mm or surface area...
April 30, 2007
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Tracking structural abnormalities is more important in early glaucoma than at the end of the disease
The Science behind the Tip Diagnosing glaucoma and documenting progression at an early stage of the disease is a key thing to successful glaucoma...
March 31, 2007
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Target pressure is now an accepted part of standard glaucoma care
The Science behind the Tip Target pressure is an estimate of the mean intraocular pressure (IOP) obtained with therapy that is expected to prevent...
December 31, 2006
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Early aggressive treatment is indicated in selected glaucoma cases
The Science behind the Tip In the Early Manifest Glaucoma Trial (EMGT)(1) patients treated had half of the progression risk of control patients....
November 30, 2006