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How do you communicate numbers to your glaucoma patient?
Shared decision making can reduce overtreatment, which places an unnecessary burden on the...
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Validating and updating the OHTS-EGPS model predicting 5-year glaucoma risk among ocular hypertension patients using electronic records
Objective: To validate and update the OHTS-EGPS model predicting risk of conversion from OHT to...
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The Strain Response to Intraocular Pressure Increase in the Lamina Cribrosa of Control Subjects and Glaucoma Patients
Purpose: The purpose of this study was to measure biomechanical strains in the lamina cribrosa...
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Psychological Stress and Intraocular Pressure in Glaucoma: A Randomized Controlled Trial
Purpose: To evaluate the intraocular pressure (IOP) behavior after applying a standardized...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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The regular (and sometimes clandestine) application of periocular corticosteroid cream can induce glaucoma in susceptible individuals
The Science behind the Tip Steroid-induced ocular hypertension and glaucoma is typically associated with topical steroid therapy and presents with...
February 28, 2017
Posner-Schlossman Syndrome
Author(s): Megaw R (1), Agarwal PK (2) 1 Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of...
February 28, 2017
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics
Author(s): Springelkamp H (1,2), Iglesias AI, Mishra A (3,4), Höhn R (5,6), Wojciechowski R, Khawaja AP (7), Nag A (8), Wang YX (9,10), Wang JJ...
February 28, 2017
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In patients with primary angle-closure glaucoma and primary angle closure with high intraocular pressure (IOP), there is a good evidence to support the use of clear lens extraction with intraocular lens implantation as initial treatment
The Science behind the Tip The standard treatment for primary angle-closure glaucoma (PACG) is laser peripheral iridotomy (PI) to open the drainage...
January 31, 2017
Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study
Author(s): Scheetz TE (1), Faga B (1), Ortega L (2), Roos BR (1), Gordon MO (3), Kass MA (3), Wang K (4), Fingert JH (5) 1 Department Ophthalmology...
January 31, 2017
Lamina cribrosa in glaucoma
Author(s): Downs JC (1), Girkin CA 1 Department of Ophthalmology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA....
January 31, 2017
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Patients with neovascular glaucoma should be referred to a general physician as management of their underlying systemic disease should increase their life expectancy
The Science behind the Tip Most patients with neovascular glaucoma have retinal ischaemia secondary to either proliferative diabetic retinopathy,...
December 31, 2016
New classes of glaucoma medications
Author(s): Schehlein EM (1), Novack GD, Robin AL 1 a University of Maryland School of Medicine, Department of Ophthalmology and Visual Sciences,...
December 31, 2016
The neuroprotective effect of latanoprost acts via klotho-mediated suppression of calpain activation after optic nerve transection
Author(s): Yamamoto K (1), Sato K (1,2), Yukita M (1), Yasuda M (1), Omodaka K (1,2), Ryu M (1), Fujita K (3), Nishiguchi KM (4), Machida S (5,6),...
December 31, 2016
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The risk of secondary haemorrhage after hyphaema can be reduced by using topical steroids and oral tranexamic acid
The Science behind the Tip A hyphaema is a common and usually innocuous consequence of blunt injury or ocular surgery. However, the secondary...
November 30, 2016
Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial
Author(s): Azuara-Blanco A (1), Burr J (2), Ramsay C (3), Cooper D (3), Foster PJ (4), Friedman DS (5), Scotland G (6), Javanbakht M (7), Cochrane...
November 30, 2016
Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine
Author(s): Fini ME (1), Schwartz SG (2), Gao X (3), Jeong S (4), Patel N (5), Itakura T (6), Price MO (7), Price FW Jr (8), Varma R (9), Stamer WD...
November 30, 2016
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Despite the increased central corneal thickness (CCT) that may follow lamellar corneal surgery, reliable IOP measurements can be obtained with Goldmann applanation tonometry or Pascal dynamic tomography
The Science behind the Tip Lamellar corneal surgery (DSAEK, DMEK) is replacing penetrating keratoplasty, because visual recovery is better and...
October 31, 2016
Monitoring ocular hypertension, how much and how often? A cost-effectiveness perspective
Author(s): Hernández R(1), Burr JM(2), Vale L(3), Azuara-Blanco A(4), Cook JA(5), Banister K(6), Tuulonen A(7), Ryan M(1); Surveillance of Ocular...
October 31, 2016
Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses
Author(s): Khawaja AP(1), Cooke Bailey JN(2), Kang JH(3), Allingham RR(4), Hauser MA(5), Brilliant M(6), Budenz DL(7), Christen WG(8), Fingert...
October 31, 2016
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In patients with pigment dispersion syndrome, YAG laser peripheral iridotomy can reduce the risk of raised intraocular pressure (IOP) in some patients, but does not prevent glaucoma
The Science behind the Tip Pigment dispersion syndrome arises from posterior bowing of the iris secondary to reverse pupil block. This causes...
September 30, 2016
The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma
Author(s): Abe RY, Diniz-Filho A, Zangwill LM, Gracitelli CP, Marvasti AH, Weinreb RN, Baig S, Medeiros FA PURPOSE: The purpose of this study was...
September 30, 2016
Glaucoma related Proteomic Alterations in Human Retina Samples
Author(s): Funke S (1), Perumal N (1), Beck S (1), Gabel-Scheurich S (1), Schmelter C (1), Teister J (1), Gerbig C (1), Gramlich OW (1,2), Pfeiffer...
September 30, 2016
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An optic disc haemorrhage indicates ongoing structural change and is an important sign of progressive glaucoma
The Science behind the Tip Prospective studies have shown that splinter-shaped haemorrhages at the optic disc margin are an important risk factor...
July 31, 2016
Importance of Normal Aging in Estimating the Rate of Glaucomatous Neuroretinal Rim and Retinal Nerve Fiber Layer Loss
Author(s): Vianna JR (1), Danthurebandara VM (1), Sharpe GP (1), Hutchison DM (1), Belliveau AC (1), Shuba LM (1), Nicolela MT (1), Chauhan BC (2)...
July 31, 2016
Predegenerated Schwann cells-a novel prospect for cell therapy for glaucoma: neuroprotection, neuroregeneration and neuroplasticity
Author(s): Smedowski A (1,2,3), Liu X (4), Pietrucha-Dutczak M (1), Matuszek I (1), Varjosalo M (4), Lewin-Kowalik J (1) 1 Chair and Department of...
July 31, 2016
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Gradual intraocular pressure (IOP) elevation with a need for additional treatment is common in pseudophakic glaucoma patients following Nd; YAG laser posterior capsulotomy
The Science behind the Tip Nd: YAG laser capsulotomy is known to increase the IOP in some normal patients in the short term, with the maximum IOP...
June 30, 2016
Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up
Author(s): Peters D (1), Heijl A (1), Brenner L (2), Bengtsson B (1) 1 Department of Ophthalmology, Skåne University Hospital, Lund University,...
June 30, 2016
Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma
Author(s): Vithana EN (1), Khor CC, Qiao C, Nongpiur ME, George R, Chen LJ, Do T, Abu-Amero K, Huang CK, Low S, Tajudin LS, Perera SA, Cheng CY, Xu...
June 30, 2016
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Early detection of hypotony maculopathy is essential, as permanent chorioretinal changes and poor visual outcomes will occur without rapid surgical intervention
The science behind the tip Hypotony maculopathy is an uncommon but serious late complication of glaucoma filtration surgery, particularly when an...
May 31, 2016