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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Various factors can result in discordance between gonioscopy and Anterior Segment Optical Coherence Tomography (AS-OCT) when assessing angle closure

    The Science behind the Tip Gonioscopy remains the gold standard for confirming iridotrabecular contact and diagnosing angle closure.1 AS-OCT and...

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    Various factors can result in discordance between gonioscopy and Anterior Segment Optical Coherence Tomography (AS-OCT) when assessing angle closure

    Various factors can result in discordance between gonioscopy and Anterior Segment Optical Coherence Tomography (AS-OCT) when assessing angle closure

    The Science behind the Tip Gonioscopy remains the gold standard for confirming iridotrabecular...

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  • Effective Treatment of Optic Neuropathies by Intraocular Delivery of MSC-sEVs through Augmenting the G-CSF-Macrophage Pathway

    Optic neuropathies, characterized by injury of retinal ganglion cell (RGC) axons of the optic nerve, cause incurable blindness worldwide....

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    Effective Treatment of Optic Neuropathies by Intraocular Delivery of MSC-sEVs through Augmenting the G-CSF-Macrophage Pathway

    Effective Treatment of Optic Neuropathies by Intraocular Delivery of MSC-sEVs through Augmenting the G-CSF-Macrophage Pathway

    Optic neuropathies, characterized by injury of retinal ganglion cell (RGC) axons of the optic...

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  • Retinal Nerve Fiber Layer Optical Texture Analysis

    PURPOSE: To apply retinal nerve fiber layer (RNFL) optical texture analysis (ROTA) to investigate the prevalence, patterns, and risk factors of...

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    Retinal Nerve Fiber Layer Optical Texture Analysis

    Retinal Nerve Fiber Layer Optical Texture Analysis

    PURPOSE: To apply retinal nerve fiber layer (RNFL) optical texture analysis (ROTA) to investigate...

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  • A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.

    PURPOSE: Glaucoma represents a pressing public health need among African ancestry individuals. This study provides novel insight into the genetic...

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    A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.

    A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.

    PURPOSE: Glaucoma represents a pressing public health need among African ancestry individuals....

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  • Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma

    Primary open-angle glaucoma (POAG), characterized by retinal ganglion cell death, is a leading cause of irreversible blindness worldwide. However,...

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    Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma

    Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma

    Primary open-angle glaucoma (POAG), characterized by retinal ganglion cell death, is a leading...

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  • Identifying a high polygenic risk for glaucoma will allow us to identify glaucoma patients at risk for rapid structural and functional glaucoma progression

    The Science behind the Tip The identification of an individual´s genetic risk of a disease is increasingly recognized as a tool in disease risk...

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    Identifying a high polygenic risk for glaucoma will allow us to identify glaucoma patients at risk for rapid structural and functional glaucoma progression

    Identifying a high polygenic risk for glaucoma will allow us to identify glaucoma patients at risk for rapid structural and functional glaucoma progression

    The Science behind the Tip The identification of an individual´s genetic risk of a disease is...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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Association Between Visual Field Damage and Gait Dysfunction in Patients With Glaucoma

Clinical paper of the month

Association Between Visual Field Damage and Gait Dysfunction in Patients With Glaucoma

Author(s): Jian-Yu E (1,2), Aleksandra Mihailovic (1), Catalina Garzon (1), Jennifer A Schrack (2,3), Tianjing Li (4), Sheila K West (1), Laura N...

November 30, 2021

Unplanned Return to the Operating Room After Trabeculectomy

Clinical paper of the month

Unplanned Return to the Operating Room After Trabeculectomy

Author(s): Nur Cardakli (1), David S Friedman (2), Michael V Boland (3) 1 Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins...

November 30, 2021

In vivo imaging of the Schlemm's Canal and the response to Selective laser trabeculoplasty

Clinical paper of the month

In vivo imaging of the Schlemm's Canal and the response to Selective laser trabeculoplasty

Author(s): Toshit Varshney (1), Kishan Azmira (1), Shikha Gupta (1), Karthikeyan Mahalingam (1), Abhishek Singh (1), Dewang Angmo (1), Viney Gupta...

October 31, 2021

Long-Term Outcomes of Selective Laser Trabeculoplasty for Open-Angle Glaucoma in the Caribbean

Clinical paper of the month

Long-Term Outcomes of Selective Laser Trabeculoplasty for Open-Angle Glaucoma in the Caribbean

Author(s): Tony Realini (1), Hazel Shillingford-Ricketts (2), Darra Burt (3), Goundappa K Balasubramani (4) 1 West Virginia University Eye...

September 30, 2021

Gonioscopy-assisted transluminal trabeculotomy (GATT) for myocilin juvenile glaucoma

Clinical paper of the month

Gonioscopy-assisted transluminal trabeculotomy (GATT) for myocilin juvenile glaucoma

Author(s): Erin A Boese (1), Wallace L M Alward (2), John H Fingert (2) Department Ophthalmology and Visual Sciences, Carver College of Medicine,...

July 31, 2021

Ab-externo MicroShunt versus Trabeculectomy in Primary Open-Angle Glaucoma: 1-year Results from a 2-year Randomized, Multicenter Study

Clinical paper of the month

Ab-externo MicroShunt versus Trabeculectomy in Primary Open-Angle Glaucoma: 1-year Results from a 2-year Randomized, Multicenter Study

Author(s): N Douglas Baker (1), Howard S Barnebey (2), Marlene R Moster (3), Michael C Stiles (4), Steven D Vold (5), Anup K Khatana (6), Brian E...

June 30, 2021

Ten-Year Clinical Outcomes of Acute Primary Angle Closure Randomized to Receive Early Phacoemulsification Versus Laser Peripheral Iridotomy

Clinical paper of the month

Ten-Year Clinical Outcomes of Acute Primary Angle Closure Randomized to Receive Early Phacoemulsification Versus Laser Peripheral Iridotomy

Author(s): Poemen P Chan (1,2), Fang Y Tang (1), Dexter Y Leung (1,3), Thomas C Lam (1,2), Nafees Baig (1,4,3), Clement C Tham (1,2,5) 1 Department...

May 31, 2021

Quality of Life in Primary Open-Angle Glaucoma and Cataract: An Analysis of VFQ-25 and OSDI from the iStent inject® Pivotal Trial

Clinical paper of the month

Quality of Life in Primary Open-Angle Glaucoma and Cataract: An Analysis of VFQ-25 and OSDI from the iStent inject® Pivotal Trial

Author(s): Thomas W Samuelson (1), Inder Paul Singh (2), Blake K Williamson (3), Heather Falvey (4), Won Chan Lee (5), Dawn Odom (6), David...

April 30, 2021

Anatomical Changes and Predictors of Angle Widening After Laser Peripheral Iridotomy: The Zhongshan Angle Closure Prevention Trial

Clinical paper of the month

Anatomical Changes and Predictors of Angle Widening After Laser Peripheral Iridotomy: The Zhongshan Angle Closure Prevention Trial

Author(s): Benjamin Y Xu (1), David S Friedman (2), Paul J Foster (3), Yu Jiang (4), Anmol A Pardeshi (5), Yuzhen Jiang (4), Beatriz Munoz (6), Tin...

February 28, 2021

Glaucoma-Related Adverse Events at 10 Years in the Infant Aphakia Treatment Study: A Secondary Analysis of a Randomized Clinical Trial

Clinical paper of the month

Glaucoma-Related Adverse Events at 10 Years in the Infant Aphakia Treatment Study: A Secondary Analysis of a Randomized Clinical Trial

Author(s): Sharon F Freedman (1), Allen D Beck (2), Azhar Nizam (3), Deborah K Vanderveen (4), David A Plager (5), David G Morrison (6), Carolyn D...

January 31, 2021

Risk Factors for Visual Field Deterioration in the United Kingdom Glaucoma Treatment Study

Clinical paper of the month

Risk Factors for Visual Field Deterioration in the United Kingdom Glaucoma Treatment Study

Author(s): Panayiota Founti (1), Catey Bunce (2), Anthony P Khawaja (3), Caroline J Doré (4), Jibran Mohamed-Noriega (3), David F Garway-Heath (3),...

December 31, 2020

Longitudinal Macular Ganglion Cell-Inner Plexiform Layer Measurements to Detect Glaucoma Progression in High Myopia

Clinical paper of the month

Longitudinal Macular Ganglion Cell-Inner Plexiform Layer Measurements to Detect Glaucoma Progression in High Myopia

Author(s): Joong Won Shin (1), Min Kyung Song (1), Kyung Rim Sung (2) 1 Department of Ophthalmology, College of Medicine, University of Ulsan, Asan...

October 31, 2020

Cardiovascular Disease may predict structural and functional progression in early glaucoma

Clinical paper of the month

Cardiovascular Disease may predict structural and functional progression in early glaucoma

Author(s): Henry Marshall (1), Sean Mullany (2), Ayub Qassim (2), Mark Hassall (2), Owen Siggs (2), Bronwyn Ridge (2), Thi Nguyen (2), Mona...

September 30, 2020

Longitudinal Macular Structure–Function Relationships in Glaucoma

Clinical paper of the month

Longitudinal Macular Structure–Function Relationships in Glaucoma

Author(s): Vahid Mohammadzadeh (1), Alessandro Rabiolo (2), Qiang Fu (3), Esteban Morales (1), Anne L Coleman (1), Simon K Law (1), Joseph Caprioli...

July 31, 2020

Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial

Clinical paper of the month

Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial

Author(s): David M.Wright (1,2), Evgenia Konstantakopoulou (3,4,5), Giovanni Montesano (6), Neil Nathwani (3), Anurag Garg (3), David Garway-Heath...

June 30, 2020

Franz Fankhauser: the father of the automated perimeter

Clinical paper of the month

Franz Fankhauser: the father of the automated perimeter

Author(s): Gloor BP Zürich, Switzerland. Franz Fankhauser is known as the father of automated perimetry and of the q-switched Nd:YAG laser knife....

May 31, 2020

The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study

Clinical paper of the month

The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study

Author(s): Newman-Casey PA (1), Niziol LM (2), Gillespie BW (3), Janz NK (4), Lichter PR (2), Musch DC (5) 1 Department of Ophthalmology and Visual...

March 31, 2020

Aniridia and Axenfeld-Rieger Syndrome: Clinical Presentations, Molecular Genetics and Current/Emerging Therapies

Clinical paper of the month

Aniridia and Axenfeld-Rieger Syndrome: Clinical Presentations, Molecular Genetics and Current/Emerging Therapies

Author(s): Paul W Chrystal (1), Michael A Walter (2) 1 Department of Medical Genetics, University of Alberta, Edmonton, AB, Canada. 2 Department of...

February 29, 2020

Human versus Machine: Comparing a Deep Learning Algorithm to Human Gradings for Detecting Glaucoma on Fundus Photographs

Clinical paper of the month

Human versus Machine: Comparing a Deep Learning Algorithm to Human Gradings for Detecting Glaucoma on Fundus Photographs

Author(s): Jammal AA (1), Thompson AC (2), Mariottoni EB (2), Berchuck SI (3), Urata CN (2), Estrela T (2), Wakil SM (2), Costa VP (4), Medeiros FA...

December 31, 2019

Glaucoma management in the era of artificial intelligence

Clinical paper of the month

Glaucoma management in the era of artificial intelligence

Author(s): Devalla SK (1), Liang Z (1), Pham TH (1,2), Boote C (1,3,4), Strouthidis NG (2,5,6), Thiery AH (7), Girard MJA (8,2) 1 Department of...

November 30, 2019

Exogenous influences on intraocular pressure

Clinical paper of the month

Exogenous influences on intraocular pressure

Author(s): Kim YW (1), Park KH (2) 1 Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea. 2 Ophthalmology, Seoul National...

October 31, 2019

Predictors of Neovascular Glaucoma in Central Retinal Vein Occlusion

Clinical paper of the month

Predictors of Neovascular Glaucoma in Central Retinal Vein Occlusion

Author(s): Rong AJ (1), Swaminathan SS (2), Vanner EA (3), Parrish RK 2nd (3) 1 Department of Ophthalmology, Bascom Palmer Eye Institute,...

September 30, 2019

Effect of trabeculectomy on corneal endothelial cell loss

Clinical paper of the month

Effect of trabeculectomy on corneal endothelial cell loss

Author(s): Hirooka K (1), Nitta E (2), Ukegawa K (2), Sato S (2), Kiuchi Y (3) 1 Ophthalmology and Visual Science, Hiroshima University, Hiroshima,...

July 31, 2019

Risk factors for disease progression in low-teens normal-tension glaucoma

Clinical paper of the month

Risk factors for disease progression in low-teens normal-tension glaucoma

Author(s): Baek SU (1,2), Ha A (3,4), Kim DW (5,6), Jeoung JW (3,4), Park KH (3,4), Kim YK (7,4) 1 Department of Ophthalmology, Hallym University...

June 30, 2019

Exogenous influences on intraocular pressure

Clinical paper of the month

Exogenous influences on intraocular pressure

Author(s): Kim YW (1), Park KH (2) 1 Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea. 2 Ophthalmology, Seoul National...

May 31, 2019