-
Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization
Purpose: Glaucoma is the primary cause of permanent vision loss worldwide. However, the...
Learn more... -
Quality of Life and Primary Open-Angle Glaucoma in the Ocular Hypertension Treatment Study
Importance: If preperimetric glaucoma reduces patient-reported vision-related quality of life...
Learn more... -
Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
Learn more... -
The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
Learn more... -
.jpg)
Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
Learn more... -
.jpg)
Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
Learn more... -
Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
Learn more... -
Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
Learn more... -
.jpg)
Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
Learn more... -
Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
Learn more... -
Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
Learn more...
.jpg)
Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells
Author(s): Feng Tian (1), Yuyan Cheng (2), Songlin Zhou (1), Qianbin Wang (1), Aboozar Monavarfeshani (3), Kun Gao (2), Weiqian Jiang (1), Riki...
July 30, 2022
.jpg)
Intelligent wireless theranostic contact lens for electrical sensing and regulation of intraocular pressure
Author(s): Cheng Yang (1), Qianni Wu (2), Junqing Liu (3), Jingshan Mo (1), Xiangling Li (1,4), Chengduan Yang (1,5), Ziqi Liu (1), Jingbo Yang...
June 30, 2022
.jpg)
Monocyte-derived SDF1 supports optic nerve regeneration and alters retinal ganglion cells' response to Pten deletion
Author(s): Lili Xie (1,2), Ling-Ping Cen (1,2 3), Yiqing Li (1,2,4), Hui-Ya Gilbert (1,2), Oleksandr Strelko (1,2), Cynthia Berlinicke (5,6,7,8),...
May 31, 2022
.jpg)
Is Genetic Risk for Sleep Apnea Causally Linked With Glaucoma Susceptibility?
Author(s): Nathan Ingold (1,2), Adrian I Campos (1,3), Xikun Han (1,3), Jue-Sheng Ong (1), Puya Gharahkhani (1), David A Mackey (4), Miguel E...
April 30, 2022
.jpg)
Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma
Author(s): Luis Alarcon-Martinez (1,2), Yukihiro Shiga (3,2), Deborah Villafranca-Baughman )3,2), Nicolas Belforte (3,2), Heberto Quintero (3,2),...
March 31, 2022
.jpg)
GWAS identifies two common loci associated with pigment dispersion syndrome/pigmentary glaucoma and implicate myopia in its development
Author(s): Mark J Simcoe (1), Ameet Shah (2), Baojian Fan (3), Hélène Choquet (4), Nicole Weisschuh (5), Naushin H Waseem (6), Chen Jiang (4),...
February 28, 2022
.jpg)
Phase 1b Randomized Controlled Study of Short Course Topical Recombinant Human Nerve Growth Factor (rhNGF) for Neuroenhancement in Glaucoma: Safety, Tolerability, and Efficacy Measure Outcomes
Author(s): Gala Beykin (1), Laurel Stell (1), Muhammad Sohail Halim (1), Mariana Nuñez (1), Lilia Popova (1), Bac T Nguyen (1), Sylvia L Groth (1),...
January 31, 2022
Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies
Author(s): Benjamin R Thomson (1,2), Pan Liu (1,2), Tuncer Onay (1), Jing Du (1,2), Stuart W Tompson (3), Sol Misener (1,2), Raj R Purohit (1,2),...
December 31, 2021
GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans
Author(s): K Saidas Nair (# 1), Chitrangda Srivastava (# 2), Robert V Brown (# 2), Swanand Koli (3), Hélène Choquet (4), Hong Soon Kang (2),...
November 30, 2021
Preservation of vision after CaMKII-mediated protection of retinal ganglion cells
Author(s): 1 Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. 2 Department of Neuroscience, Yale...
October 31, 2021
Agonist of growth hormone-releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury
Author(s): Ling-Ping Cen (1), Tsz Kin Ng (1,2,3), Jia-Jian Liang (1), Ciyan Xu (1), Xi Zhuang (1), Yu-Fen Liu (1,2), Shao-Lang Chen (1), Yanxuan Xu...
September 30, 2021
A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure
Author(s): Guorong Li (1), Astrid F Nottebaum (2), Mitchell Brigell (3), Iris D Navarro (1), Ute Ipe (2), Sarthak Mishra (2), Maria Gomez-Caraballo...
July 31, 2021
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma
Author(s): Pinkal D Patel (1), Yen-Lin Chen (2), Ramesh B Kasetti (1), Prabhavathi Maddineni (1), William Mayhew (1), J Cameron Millar (1), Dorette...
June 30, 2021
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries
Author(s): Puya Gharahkhani (1), Eric Jorgenson (2), Pirro Hysi (3), Anthony P Khawaja (4,5), Sarah Pendergrass (6) et al. 1 QIMR Berghofer Medical...
May 31, 2021
Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye
Author(s): Genetics of Exfoliation Syndrome Partnership For a full list of authors and affiliations please visit...
April 30, 2021
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS
Author(s): Veselina Petrova (1), Craig S Pearson (2), Jared Ching (3,4,5), James R Tribble (6), Andrea G Solano (2), Yunfei Yang (5), Fiona M Love...
March 31, 2021
Longitudinal Changes in Macular Optical Coherence Tomography Angiography Metrics in Primary Open-Angle Glaucoma With High Myopia: A Prospective Study
Author(s): Fengbin Lin (1), Fei Li (1), Kai Gao (1), Wanbing He (1), Jun Zeng (1), Yu Chen (1), Meiling Chen (1), Weijing Cheng (1), Yunhe Song...
February 28, 2021
Peripapillary sclera exhibits a v-shaped configuration that is more pronounced in glaucoma eyes
Author(s): Xiaofei Wang (1), Tin A Tun (2,3), Monisha Esther Nongpiur (3,4), Hla M Htoon (3), Yih Chung Tham (3), Nicholas G Strouthidis (5,6), Tin...
January 31, 2021
Metabolomic profiling of aqueous humor from glaucoma patients - The metabolomics in surgical ophthalmological patients (MISO) study
Author(s): João Barbosa Breda (1), Anca Croitor Sava (2), Uwe Himmelreich (2), Alix Somers (3), Christophe Matthys (4), Amândio Rocha Sousa (5),...
December 31, 2020
Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases
Author(s): Bryn L Brazile (1), Bin Yang (1,2), Susannah Waxman (1) , Po Lam (1), Andrew P Voorhees (1), Yi Hua (1), Ralitsa T Loewen (1), Nils A...
October 31, 2020
Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study
Author(s): Xiaoran Chai (1,2,3), Kok Yao Low (1,4), Yih Chung Tham (1), Miao Li Chee (1), Sahil Thakur (1), Liang Zhang (1), Nicholas Y Tan (1),...
September 30, 2020
Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems
Author(s): Hee Kyung Yang (1), Young Jae Kim (2), Jae Yun Sung (1), Dong Hyun Kim (1), Kwang Gi Kim (3), Jeong-Min Hwang (4) 1 Department of...
July 31, 2020
Using Deep Learning to Automate Goldmann Applanation Tonometry Readings
Author(s): Ted Spaide (1), Yue Wu (1), Ryan T Yanagihara (1), Shu Feng (1), Omar Ghabra (1), Jonathan S Yi (1), Philip P Chen (1), Francy Moses...
June 30, 2020
Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System
Author(s): Ikegami K, Shigeyoshi Y, Masubuchi S PURPOSE: Elevated IOP can cause the development of glaucoma. The circadian rhythm of IOP depends on...
May 31, 2020
Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry
Author(s): Genetics of Glaucoma in People of African Descent (GGLAD) Consortium, Hauser MA (1,2,3,4), Allingham RR (2,3,4), Aung T (3,4,5,6), Van...
March 31, 2020