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  • Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate their impact on success rates. DESIGN: Systematic...

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    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate...

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  • A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health conditions in retinal images and expediting the...

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    A foundation model for generalizable disease detection from retinal images

    A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health...

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  • Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation compares medical and surgical management...

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    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation...

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  • Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT) has brought attention to rare side effects such as...

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    Beware of acute corneal oedema after SLT in selected patients

    Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT)...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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When prescribing Latanoprost, don’t forget about potential cardiovascular side effects

Tip of the month

When prescribing Latanoprost, don’t forget about potential cardiovascular side effects

Prostaglandin analogues are advised as first line treatment for chronic open angle glaucoma by the European Glaucoma Society Guidelines for their...

February 28, 2022

Unilateral ocular hypertension: have a look at the corneal endothelium

Tip of the month

Unilateral ocular hypertension: have a look at the corneal endothelium

Unilateral ocular hypertension or glaucoma is often associated with secondary causes that should be explored to ascertain the visual prognosis and...

January 31, 2022

Mind the depth – forward displacement of the lens-iris diaphragm and myopic shift after ophthalmic surgery is suggestive of aqueous misdirection

Tip of the month

Mind the depth – forward displacement of the lens-iris diaphragm and myopic shift after ophthalmic surgery is suggestive of aqueous misdirection

Aqueous misdirection is a serious condition with potentially higher prevalence than expected. Predominantly observed after ocular surgery,...

December 31, 2021

Exfoliation (pseudoexfoliation) syndrome (with or without glaucoma) is associated with clinically significant non-vascular systemic diseases

Tip of the month

Exfoliation (pseudoexfoliation) syndrome (with or without glaucoma) is associated with clinically significant non-vascular systemic diseases

The association of systemic vascular dysfunction and vascular diseases with exfoliation syndrome have been extensively studied in the last decades....

December 01, 2021

Consider trabeculectomy as initial treatment for newly diagnosed advanced primary open angle glaucoma (POAG)

Tip of the month

Consider trabeculectomy as initial treatment for newly diagnosed advanced primary open angle glaucoma (POAG)

IOP control is of uttermost importance in advanced glaucoma to prevent blindness. The EGS guidelines recommend IOP in the low teens, e.g. 10-12mmHg...

October 31, 2021

Take a look at the deviation maps when assessing structural change in glaucoma

Tip of the month

Take a look at the deviation maps when assessing structural change in glaucoma

The structural analysis of the thickness of peripapillary retinal nerve fiber layer (pRNFL) and the inner layers of the posterior pole with optical...

September 30, 2021

In patients with unilateral angle recession glaucoma, the non-traumatized fellow eye should also be periodically checked

Tip of the month

In patients with unilateral angle recession glaucoma, the non-traumatized fellow eye should also be periodically checked

Angle recession (AR) is a common complication after a blunt ocular trauma, and it is related to a higher risk of developing late-onset glaucoma...

July 31, 2021

Consider Charles Bonnet syndrome in glaucoma patients even if visual acuity is still good

Tip of the month

Consider Charles Bonnet syndrome in glaucoma patients even if visual acuity is still good

Charles Bonnet syndrome (CBS) describes the presence of complex visual hallucinations with retained insight in the unreal nature of the phenomenon...

June 30, 2021

Consider focal pressure in case of poor filtration shortly after trabeculectomy

Tip of the month

Consider focal pressure in case of poor filtration shortly after trabeculectomy

Achieving a good filtration in the early postoperative period after trabeculectomy is associated with the procedure's long-term success (1)....

May 31, 2021

Ganglion cell-inner plexiform layer examination can help diagnose glaucoma in high myopia

Tip of the month

Ganglion cell-inner plexiform layer examination can help diagnose glaucoma in high myopia

Myopia can be associated with significant structural changes in the eye, including peripapillary atrophy, myopic macular degeneration and the...

April 30, 2021

My personal way to estimate whether a patient is at risk for wipeout following glaucoma surgery, is to perform a confrontation visual field with a red-topped bottle

Tip of the month

My personal way to estimate whether a patient is at risk for wipeout following glaucoma surgery, is to perform a confrontation visual field with a red-topped bottle

This should be done monocularly with the bottle moved from the area of scotoma towards fixation. One must ensure that the patient is constantly...

March 31, 2021

Consider IOP monitoring and prophylactic treatment in patients undergoing repeat intravitreal anti-VEGF injections

Tip of the month

Consider IOP monitoring and prophylactic treatment in patients undergoing repeat intravitreal anti-VEGF injections

Intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections are now in widespread use for a plethora of retinal diseases. It is...

February 28, 2021

In glaucoma patients with anterior uveitis using brimonidine, one must consider `brimonidine-associated uveitis` to avoid misdiagnosis and over-treatment

Tip of the month

In glaucoma patients with anterior uveitis using brimonidine, one must consider `brimonidine-associated uveitis` to avoid misdiagnosis and over-treatment

Raised intraocular pressure (IOP) and secondary glaucoma due to underlying uveitis is a well-acknowledged phenomenon (1). The clinician should...

January 31, 2021

The side effects of timolol and other beta-adrenergic antagonists on the cardiovascular and pulmonary system in predisposed patients should not be underestimated

Tip of the month

The side effects of timolol and other beta-adrenergic antagonists on the cardiovascular and pulmonary system in predisposed patients should not be underestimated

Since 1976 beta-adrenergic antagonists have established their role in the effective lowering of the intraocular pressure. The potential side...

December 31, 2020

Trabecular meshwork bypass surgery should be avoided if high episcleral venous pressure is suspected

Tip of the month

Trabecular meshwork bypass surgery should be avoided if high episcleral venous pressure is suspected

The intraocular pressure lowering effect of procedures that attempt to enhance flow of aqueous into Schlemm’s canal by bypassing or cutting the...

November 30, 2020

Haemodialysis can cause an acute rise in intraocular pressure

Tip of the month

Haemodialysis can cause an acute rise in intraocular pressure

Haemodialysis (HD) can reportedly induce a sudden rise in intraocular pressure (IOP) in patients with neovascular (NVG) (1) and pseudo-exfoliative...

October 31, 2020

Glaucoma progression: watch out the fellow, non-progressing eye

Tip of the month

Glaucoma progression: watch out the fellow, non-progressing eye

In clinical practice, the detection of visual field progression in one eye usually leads to management modifications in that eye. Less attention is...

September 30, 2020

Take care not to miss glaucomatous cupping in patients with small discs!

Tip of the month

Take care not to miss glaucomatous cupping in patients with small discs!

The Science behind the Tip The diagnosis of glaucoma can be missed in patients with small optic discs (1). In such patients, relative crowding of...

July 31, 2020

Ask your glaucoma patients about mobility rather than vision

Tip of the month

Ask your glaucoma patients about mobility rather than vision

The Science behind the Tip Self-reported visual disability in glaucoma which correlates with level of visual field loss includes bumping into...

June 30, 2020

Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic

Tip of the month

Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic

The Science behind the Tip The prevalence of ocular surface disease is significantly higher in glaucoma patients (1). While generally accepted that...

May 31, 2020

Late in-the-bag intraocular lens dislocation several years after uncomplicated cataract surgery is relatively common in pseudoexfoliation

Tip of the month

Late in-the-bag intraocular lens dislocation several years after uncomplicated cataract surgery is relatively common in pseudoexfoliation

The Science behind the Tip In pseudoexfoliation syndrome (PSX) and pseudoexfoliative glaucoma (PSG) progressive zonular damage frequently leads to...

March 31, 2020

Consider Brinzolamide to prevent IOP Spikes after Cataract Surgery in Eyes with Glaucoma

Tip of the month

Consider Brinzolamide to prevent IOP Spikes after Cataract Surgery in Eyes with Glaucoma

The Science behind the Tip IOP spikes, i.e. an IOP elevation after surgery compared to baseline, often occur in eyes with glaucoma.2 IOP spikes may...

February 28, 2020

Consider using a topical NSAID, or steroid, post SLT laser

Tip of the month

Consider using a topical NSAID, or steroid, post SLT laser

The Science behind the Tip There is widespread variation in post laser treatment regimes. In a recent randomized, double-masked, multi-center...

October 31, 2019