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  • Tip: Not every peripapillary hemorrhage is a sign for glaucoma

    The Science behind the Tip Most of the time, disc hemorrhages in patients with glaucoma are related to the disease itself. Although the strong...

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    Tip: Not every peripapillary hemorrhage is a sign for glaucoma

    Tip: Not every peripapillary hemorrhage is a sign for glaucoma

    The Science behind the Tip Most of the time, disc hemorrhages in patients with glaucoma are...

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  • The Factors Affecting the Stability of IOP Homeostasis

    Purpose: Shear-induced nitric oxide (NO) production by Schlemm's canal (SC) endothelial cells provides a fast, IOP-sensitive feedback signal that...

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    The Factors Affecting the Stability of IOP Homeostasis

    The Factors Affecting the Stability of IOP Homeostasis

    Purpose: Shear-induced nitric oxide (NO) production by Schlemm's canal (SC) endothelial cells...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Neuroprotection for glaucoma: Requirements for clinical translation

Clinical paper of the month

Neuroprotection for glaucoma: Requirements for clinical translation

Author(s): Levin LA (1), Crowe ME (2), Quigley HA (3); Lasker/IRRF Initiative on Astrocytes and Glaucomatous Neurodegeneration Participants 1...

May 31, 2017

The challenge of regenerative therapies for the optic nerve in glaucoma

Clinical paper of the month

The challenge of regenerative therapies for the optic nerve in glaucoma

Author(s): Calkins DJ (1), Pekny M (2), Cooper ML (3), Benowitz L (4); Lasker/IRRF Initiative on Astrocytes and Glaucomatous Neurodegeneration...

March 31, 2017

Posner-Schlossman Syndrome

Clinical paper of the month

Posner-Schlossman Syndrome

Author(s): Megaw R (1), Agarwal PK (2) 1 Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of...

February 28, 2017

Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study

Clinical paper of the month

Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study

Author(s): Scheetz TE (1), Faga B (1), Ortega L (2), Roos BR (1), Gordon MO (3), Kass MA (3), Wang K (4), Fingert JH (5) 1 Department Ophthalmology...

January 31, 2017

New classes of glaucoma medications

Clinical paper of the month

New classes of glaucoma medications

Author(s): Schehlein EM (1), Novack GD, Robin AL 1 a University of Maryland School of Medicine, Department of Ophthalmology and Visual Sciences,...

December 31, 2016

Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial

Clinical paper of the month

Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial

Author(s): Azuara-Blanco A (1), Burr J (2), Ramsay C (3), Cooper D (3), Foster PJ (4), Friedman DS (5), Scotland G (6), Javanbakht M (7), Cochrane...

November 30, 2016

Monitoring ocular hypertension, how much and how often? A cost-effectiveness perspective

Clinical paper of the month

Monitoring ocular hypertension, how much and how often? A cost-effectiveness perspective

Author(s): Hernández R(1), Burr JM(2), Vale L(3), Azuara-Blanco A(4), Cook JA(5), Banister K(6), Tuulonen A(7), Ryan M(1); Surveillance of Ocular...

October 31, 2016

The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma

Clinical paper of the month

The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma

Author(s): Abe RY, Diniz-Filho A, Zangwill LM, Gracitelli CP, Marvasti AH, Weinreb RN, Baig S, Medeiros FA PURPOSE: The purpose of this study was...

September 30, 2016

Importance of Normal Aging in Estimating the Rate of Glaucomatous Neuroretinal Rim and Retinal Nerve Fiber Layer Loss

Clinical paper of the month

Importance of Normal Aging in Estimating the Rate of Glaucomatous Neuroretinal Rim and Retinal Nerve Fiber Layer Loss

Author(s): Vianna JR (1), Danthurebandara VM (1), Sharpe GP (1), Hutchison DM (1), Belliveau AC (1), Shuba LM (1), Nicolela MT (1), Chauhan BC (2)...

July 31, 2016

Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up

Clinical paper of the month

Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up

Author(s): Peters D (1), Heijl A (1), Brenner L (2), Bengtsson B (1) 1 Department of Ophthalmology, Skåne University Hospital, Lund University,...

June 30, 2016

Diabetes, Triglyceride Levels, and Other Risk Factors for Glaucoma in the National Health and Nutrition Examination Survey 2005-2008

Clinical paper of the month

Diabetes, Triglyceride Levels, and Other Risk Factors for Glaucoma in the National Health and Nutrition Examination Survey 2005-2008

Author(s): Ko F (1), Boland MV (2), Gupta P (3), Gadkaree SK (4), Vitale S (5), Guallar E (6), Zhao D (6), Friedman DS (7) 1 Glaucoma, Moorfields...

May 31, 2016

The Pathogenesis of Raised Intraocular Pressure in Uveitis

Clinical paper of the month

The Pathogenesis of Raised Intraocular Pressure in Uveitis

Author(s): Baneke AJ (1), Lim KS (1), Stanford M (1) 1 a Department of Ophthalmology , St Thomas' Hospital, Guy's and St Thomas' NHS Trust , London...

April 30, 2016

Rate and Pattern of Rim Area Loss in Healthy and Progressing Glaucoma Eyes

Clinical paper of the month

Rate and Pattern of Rim Area Loss in Healthy and Progressing Glaucoma Eyes

Author(s): Hammel N (1), Belghith A (1), Bowd C (1), Medeiros FA (1), Sharpsten L (1), Mendoza N (1), Tatham AJ (1), Khachatryan N (1), Liebmann JM...

March 31, 2016

Microstructure of Peripapillary Atrophy and Subsequent Visual Field Progression in Treated Primary Open-Angle Glaucoma

Clinical paper of the month

Microstructure of Peripapillary Atrophy and Subsequent Visual Field Progression in Treated Primary Open-Angle Glaucoma

Author(s): Yamada H (1), Akagi T (2), Nakanishi H (1), Ikeda HO (1), Kimura Y (1), Suda K (1), Hasegawa T (1), Yoshikawa M (1), Iida Y (1),...

January 31, 2016

Trabeculectomy Can Improve Long-Term Visual Function in Glaucoma

Clinical paper of the month

Trabeculectomy Can Improve Long-Term Visual Function in Glaucoma

Author(s): Caprioli J (1), de Leon JM (2), Azarbod P (2), Chen A (2), Morales E (2), Nouri-Mahdavi K (2), Coleman A (2), Yu F (3), Afifi A (4) 1...

December 31, 2015

Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up

Clinical paper of the month

Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up

Author(s): Peters D (1), Heijl A (1), Brenner L (2), Bengtsson B (1) 1 Department of Ophthalmology, Skåne University Hospital, Lund University,...

November 30, 2015

Association between Platelet Function and Disc Hemorrhage in Patients with Normal Tension Glaucoma: A prospective cross-sectional study

Clinical paper of the month

Association between Platelet Function and Disc Hemorrhage in Patients with Normal Tension Glaucoma: A prospective cross-sectional study

Author(s): Shim SH (1), Kim JM (2), Woo HY (3), Shin KU (1), Koh JW (4), Park KH (5) 1 Department of Ophthalmology, Kangbuk Samsung Hospital,...

October 31, 2015

Patterns of Glaucoma Medication Adherence over Four Years of Follow-Up

Clinical paper of the month

Patterns of Glaucoma Medication Adherence over Four Years of Follow-Up

Author(s): Newman-Casey PA (1), Blachley T (2), Lee PP (3), Heisler M (4), Farris KB (5), Stein JD (3) 1 Department of Ophthalmology and Visual...

September 30, 2015

Relationship Between Daytime Variability of Blood Pressure or Ocular Perfusion Pressure and Glaucomatous Visual Field Progression

Clinical paper of the month

Relationship Between Daytime Variability of Blood Pressure or Ocular Perfusion Pressure and Glaucomatous Visual Field Progression

Author(s): Lee J (1), Choi J (2), Jeong D (1), Kim S (1), Kook MS (3) 1 Department of Ophthalmology, College of Medicine, University of Ulsan, Asan...

July 31, 2015

Structure-Function Relationship Between Bruch's Membrane Opening-Based Optic Nerve Head Parameters and Visual Field Defects in Glaucoma

Clinical paper of the month

Structure-Function Relationship Between Bruch's Membrane Opening-Based Optic Nerve Head Parameters and Visual Field Defects in Glaucoma

Author(s): Muth DR, Hirneiß CW PURPOSE: This study was performed to evaluate the structure-function relationship between Bruch's membrane opening...

June 30, 2015

Primary congenital glaucoma outcomes: lessons from 23 years of follow-up

Clinical paper of the month

Primary congenital glaucoma outcomes: lessons from 23 years of follow-up

Author(s): Zagora SL(1), Funnell CL(2), Martin FJ(3), Smith JE(3), Hing S(4), Billson FA(3), Veillard AS(5), Jamieson RV(6), Grigg JR(7) 1...

May 31, 2015

Lamina cribrosa depth in different stages of glaucoma

Clinical paper of the month

Lamina cribrosa depth in different stages of glaucoma

Author(s): Park SC, Brumm J, Furlanetto RL, Netto C, Liu Y, Tello C, Liebmann JM, Ritch R 1 Department of Ophthalmology, Manhattan Eye, Ear and...

April 30, 2015

Facts and myths of cerebrospinal fluid pressure for the physiology of the eye

Clinical paper of the month

Facts and myths of cerebrospinal fluid pressure for the physiology of the eye

Author(s): Jonas JB (1), Wang NL (2), Yang D (3), Ritch R (4), Panda-Jonas S (5) 1 Department of Ophthalmology, Medical Faculty Mannheim of the...

March 31, 2015

Long-Term Follow-up in Preperimetric Open-Angle Glaucoma: Progression Rates and Associated Factors

Clinical paper of the month

Long-Term Follow-up in Preperimetric Open-Angle Glaucoma: Progression Rates and Associated Factors

Author(s): Kim KE(1), Jeoung JW(2), Kim DM(1), Ahn SJ(3), Park KH(1), Kim SH(4) 1 Department of Ophthalmology, Seoul National University College of...

February 28, 2015

The impact of lack of government insured routine eye examinations on the incidence of self-reported glaucoma, cataracts and vision loss

Clinical paper of the month

The impact of lack of government insured routine eye examinations on the incidence of self-reported glaucoma, cataracts and vision loss

Author(s): Chan CH (1), Trope GE (2), Badley EM (3), Buys Y (4), Jin YP (5) 1 Division of Health Care and Outcomes Research, Toronto Western...

January 31, 2015