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Tip: Not every peripapillary hemorrhage is a sign for glaucoma
The Science behind the Tip Most of the time, disc hemorrhages in patients with glaucoma are...
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The Factors Affecting the Stability of IOP Homeostasis
Purpose: Shear-induced nitric oxide (NO) production by Schlemm's canal (SC) endothelial cells...
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Short-term Detection of Fast Progressors in Glaucoma: The Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study
Purpose: To evaluate the performance of an intensive, clustered testing approach in identifying...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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Disc Haemorrhages
The Science behind the Tip Although described most commonly in normal tension glaucoma, optic disc haemorrhages may occur in all forms of glaucoma....
April 30, 2010
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When should neuroradiological imaging be undertaken in patients with normal tension glaucoma?
The Science behind the Tip Clinicians must remain vigilant to detect intracranial pathology in patients with normal tension glaucoma. Most patients...
March 31, 2010
Simvastatin and Disease Stabilization in Normal Tension Glaucoma: A Cohort Study.
Author(s): Leung DY, Li FC, Kwong YY, Tham CC, Chi SC, Lam DS. Department of Ophthalmology and Visual Sciences, The Chinese University of Hong...
March 31, 2010
Episcleral Venous Pressure Responses to Topical Nitroprusside and N-Nitro-L-arginine Methyl Ester.
Author(s): Zamora DO, Kiel JW. Department of Ophthalmology, University of Texas Health Science Center, San Antonio, Texas. PURPOSE: To determine...
March 31, 2010
Cerebrospinal Fluid Pressure in Glaucoma A Prospective Study.
Author(s): Ren R, Jonas JB, Tian G, Zhen Y, Ma K, Li S, Wang H, Li B, Zhang X, Wang N Beijing Institute of Ophthalmology, Beijing Tongren Eye...
February 28, 2010
Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation.
Author(s): Tezel G, Yang X, Luo C, Cai J, Kain AD, Powell DW, Kuehn MH, Pierce WM Department of Ophthalmology and Visual Sciences, University of...
February 28, 2010
Prediction of glaucomatous visual field loss by extrapolation of linear trends
Author(s): Bengtsson B, Patella VM, Heijl A Departments of Clinical Sciences and Ophthalmology, Lund University, Malmö University Hospital,...
January 31, 2010
Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration
Author(s): Salinas-Navarro M, Alarcón-Martínez L, Valiente-Soriano FJ, Jiménez-López M, Mayor-Torroglosa S, Avilés-Trigueros M, Villegas-Pérez MP,...
January 31, 2010
Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study
Author(s): Topouzis F, Harris A, Wilson MR, Koskosas A, Founti P, Yu F, Anastasopoulos E, Pappas T, Coleman AL Department of Ophthalmology, School...
November 30, 2009
Complex antibody profile changes in an experimental autoimmune glaucoma animal model
Author(s): Joachim SC, Grus FH, Kraft D, White-Farrar K, Barnes G, Barbeck M, Ghanaati S, Cao S, Li B, Wax MB Experimental Ophthalmology,...
October 31, 2009
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Glaucoma medications may harm the foetus and neonate
The Science behind the Tip Human data on adverse effects of glaucoma medications during pregnancy and lactation are sparse because the coincidence...
May 31, 2009
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Intraocular pressure is overestimated in eyes with a thick cornea
The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of Goldmann applanation tonometry (GAT)(1). The...
April 30, 2009
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A thin cornea is a risk factor for primary open-angle glaucoma
The Science behind the Tip Central corneal thickness (CCT) varies among individuals, the average CCT in the general population being approximately...
March 31, 2009
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Intraocular pressure is underestimated in eyes with a thin cornea
The Science behind the Tip Variability in central corneal thickness (CCT) is a potent confounder of applanation tonometry techniques such as...
February 28, 2009
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Visual field defects are filled-in by the brain
The Science behind the Tip Contrary to long held beliefs, cortical maps in the brain are not rigid. Extensive reorganization (i.e. brain remapping)...
January 31, 2009
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Pseudoexfoliation glaucoma has a strong genetic component
Publishing date: December 2008 The Science behind the Tip Pseudoexfoliation or exfoliation syndrome (PEX) is the most common identifiable condition...
December 31, 2008
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Chase the family of primary-open angle glaucoma patients
The Science behind the Tip Various modes of screening for primary open-angle glaucoma (POAG), i.e. different combinations of tonometry and...
November 30, 2008
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Intraocular pressure should be monitored after an acute episode of angle-closure
The Science behind the Tip Treatment of acute attacks of angle-closure glaucoma induced by pupillary block is based on medical therapy aiming at...
October 31, 2008
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Topical medication may accelerate cataract formation
The Science behind the Tip A number of large studies have linked use of topical glaucoma medication with increased risk of nuclear cataract, the...
September 30, 2008
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Closing the eyes as an alternative for nasolacrimal duct occlusion
The Science behind the Tip The Science behind the Tip Manual nasolacrimal occlusion after eye drop instillation is often taught to glaucoma...
June 30, 2008
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There is no significant association between use of β-blockers and depression
The Science behind the Tip The Science behind the Tip The methodological quality of early studies of the association of systemic or topical...
May 31, 2008
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Trabeculectomy significantly increases the incidence of cataract formation
The Science behind the Tip The Science behind the Tip It is widely acknowledged that trabeculectomy (TRAB) accelerates cataract formation. The...
April 30, 2008
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Concomitant therapy with Cosopt® and Diamox® is not useful
The Science behind the Tip Although the ß-blocker timolol and the topical carbonic anhydrase inhibitor (CAI) dorzolamide both act by decreased...
March 31, 2008
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Rate of false positive answers is the only reliable reliability parameter in computerized perimetry
The Science behind the Tip In computerized perimetry patient?s reliability is measured by 3 parameters, namely rate of false positive and false...
February 29, 2008
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Normal intraocular pressure in an eye with central retinal vein occlusion does not rule out associated glaucoma
The Science behind the Tip Ocular hypertension (OH) and primary open-angle glaucoma (POAG) are strongly associated with (hemi)central retinal vein...
January 31, 2008