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  • Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate their impact on success rates. DESIGN: Systematic...

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    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate...

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  • A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health conditions in retinal images and expediting the...

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    A foundation model for generalizable disease detection from retinal images

    A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health...

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  • Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation compares medical and surgical management...

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    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation...

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  • Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT) has brought attention to rare side effects such as...

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    Beware of acute corneal oedema after SLT in selected patients

    Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT)...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases

Experimental Paper of the Month

Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases

Author(s): Bryn L Brazile (1), Bin Yang (1,2), Susannah Waxman (1) , Po Lam (1), Andrew P Voorhees (1), Yi Hua (1), Ralitsa T Loewen (1), Nils A...

October 31, 2020

Malignant glaucoma

Pearl

Malignant glaucoma

Pearls Manager: Andrew Tatham Malignant glaucoma or aqueous misdirection is a rare type of secondary angle closure glaucoma most commonly...

October 20, 2020

Angle Closure - Relevant breakthroughs in this field

SIG Corner

Angle Closure - Relevant breakthroughs in this field

2.1 Should laser peripheral iridotomy (LPI) be performed in primary angle-closure suspect (PACS) patients? Last year we covered the EAGLE and ZAP...

October 01, 2020

Glaucoma progression: watch out the fellow, non-progressing eye

Tip of the month

Glaucoma progression: watch out the fellow, non-progressing eye

In clinical practice, the detection of visual field progression in one eye usually leads to management modifications in that eye. Less attention is...

September 30, 2020

Cardiovascular Disease may predict structural and functional progression in early glaucoma

Clinical paper of the month

Cardiovascular Disease may predict structural and functional progression in early glaucoma

Author(s): Henry Marshall (1), Sean Mullany (2), Ayub Qassim (2), Mark Hassall (2), Owen Siggs (2), Bronwyn Ridge (2), Thi Nguyen (2), Mona...

September 30, 2020

Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study

Experimental Paper of the Month

Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study

Author(s): Xiaoran Chai (1,2,3), Kok Yao Low (1,4), Yih Chung Tham (1), Miao Li Chee (1), Sahil Thakur (1), Liang Zhang (1), Nicholas Y Tan (1),...

September 30, 2020

Mutations in SPATA13/ASEF2 Cause Primary Angle Closure Glaucoma

NGP Paper

Mutations in SPATA13/ASEF2 Cause Primary Angle Closure Glaucoma

Author(s): Naushin H Waseem (1), Sancy Low (2,3,4), Amna Z Shah (3), Deepa Avisetti (5), Pia Ostergaard (6), Michael Simpson (7), Katarzyna A...

September 30, 2020

Optimising eye drop instillation

Pearl

Optimising eye drop instillation

Pearls Manager: Andrew Tatham When two eye drops are instilled 30 seconds apart, almost 50% of the first drug will be washed out. It is recommended...

September 30, 2020

Take care not to miss glaucomatous cupping in patients with small discs!

Tip of the month

Take care not to miss glaucomatous cupping in patients with small discs!

The Science behind the Tip The diagnosis of glaucoma can be missed in patients with small optic discs (1). In such patients, relative crowding of...

July 31, 2020

Longitudinal Macular Structure–Function Relationships in Glaucoma

Clinical paper of the month

Longitudinal Macular Structure–Function Relationships in Glaucoma

Author(s): Vahid Mohammadzadeh (1), Alessandro Rabiolo (2), Qiang Fu (3), Esteban Morales (1), Anne L Coleman (1), Simon K Law (1), Joseph Caprioli...

July 31, 2020

Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems

Experimental Paper of the Month

Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems

Author(s): Hee Kyung Yang (1), Young Jae Kim (2), Jae Yun Sung (1), Dong Hyun Kim (1), Kwang Gi Kim (3), Jeong-Min Hwang (4) 1 Department of...

July 31, 2020

The Collaborative Normal Tension Glaucoma Study (CNTGS)

Pearl

The Collaborative Normal Tension Glaucoma Study (CNTGS)

Pearls Manager: Andrew Tatham The CNTGS compared treatment versus no treatment in patients with normal tension glaucoma who had verified...

July 30, 2020

Ask your glaucoma patients about mobility rather than vision

Tip of the month

Ask your glaucoma patients about mobility rather than vision

The Science behind the Tip Self-reported visual disability in glaucoma which correlates with level of visual field loss includes bumping into...

June 30, 2020

Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial

Clinical paper of the month

Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial

Author(s): David M.Wright (1,2), Evgenia Konstantakopoulou (3,4,5), Giovanni Montesano (6), Neil Nathwani (3), Anurag Garg (3), David Garway-Heath...

June 30, 2020

Using Deep Learning to Automate Goldmann Applanation Tonometry Readings

Experimental Paper of the Month

Using Deep Learning to Automate Goldmann Applanation Tonometry Readings

Author(s): Ted Spaide (1), Yue Wu (1), Ryan T Yanagihara (1), Shu Feng (1), Omar Ghabra (1), Jonathan S Yi (1), Philip P Chen (1), Francy Moses...

June 30, 2020

Wound healing is one of the main determinants of long-term intraocular pressure control after filtering surgery

Pearl

Wound healing is one of the main determinants of long-term intraocular pressure control after filtering surgery

Pearls Manager: Andrew Tatham Risk factors for conjunctival scarring include young age, African ancestry, inflammatory eye disease, long-term...

June 18, 2020

Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic

Tip of the month

Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic

The Science behind the Tip The prevalence of ocular surface disease is significantly higher in glaucoma patients (1). While generally accepted that...

May 31, 2020

Franz Fankhauser: the father of the automated perimeter

Clinical paper of the month

Franz Fankhauser: the father of the automated perimeter

Author(s): Gloor BP Zürich, Switzerland. Franz Fankhauser is known as the father of automated perimetry and of the q-switched Nd:YAG laser knife....

May 31, 2020

Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System

Experimental Paper of the Month

Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System

Author(s): Ikegami K, Shigeyoshi Y, Masubuchi S PURPOSE: Elevated IOP can cause the development of glaucoma. The circadian rhythm of IOP depends on...

May 31, 2020

Individualized glaucoma treatment

Pearl

Individualized glaucoma treatment

Pearls Manager: Andrew Tatham Individualized glaucoma treatment aims at providing glaucoma management tailored to the individual needs of the...

May 30, 2020

Exfoliation SIG

SIG Corner

Exfoliation SIG

Chair: Gabor Hollo Co-chair: Anastasios Konstas The goal of this SIG is to increase ophthalmologists’ knowledge on XFS and XFG, and to support the...

May 24, 2020

Late in-the-bag intraocular lens dislocation several years after uncomplicated cataract surgery is relatively common in pseudoexfoliation

Tip of the month

Late in-the-bag intraocular lens dislocation several years after uncomplicated cataract surgery is relatively common in pseudoexfoliation

The Science behind the Tip In pseudoexfoliation syndrome (PSX) and pseudoexfoliative glaucoma (PSG) progressive zonular damage frequently leads to...

March 31, 2020

The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study

Clinical paper of the month

The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study

Author(s): Newman-Casey PA (1), Niziol LM (2), Gillespie BW (3), Janz NK (4), Lichter PR (2), Musch DC (5) 1 Department of Ophthalmology and Visual...

March 31, 2020

Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry

Experimental Paper of the Month

Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry

Author(s): Genetics of Glaucoma in People of African Descent (GGLAD) Consortium, Hauser MA (1,2,3,4), Allingham RR (2,3,4), Aung T (3,4,5,6), Van...

March 31, 2020

Care Delivery SIG

SIG Corner

Care Delivery SIG

SIG Corner Editor: João Barbosa Breda Chair: Anton B. Hommer Co-chair: Gábor Holló The goal of this SIG is to keep an updated overview of glaucoma...

March 31, 2020