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  • Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate their impact on success rates. DESIGN: Systematic...

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    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success

    PURPOSE: Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate...

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  • A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health conditions in retinal images and expediting the...

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    A foundation model for generalizable disease detection from retinal images

    A foundation model for generalizable disease detection from retinal images

    Medical artificial intelligence (Al) offers great potential for recognizing signs of health...

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  • Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation compares medical and surgical management...

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    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma

    Synopsis: Advanced glaucoma is associated with sight loss. This within-trial economic evaluation...

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  • Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT) has brought attention to rare side effects such as...

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    Beware of acute corneal oedema after SLT in selected patients

    Beware of acute corneal oedema after SLT in selected patients

    The Science behind the Tip The increase in the practice of selective laser trabeculoplasty (SLT)...

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  • The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with many individuals living with more than one illness....

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    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    The relationship between multiple deprivation and severity of glaucoma at diagnosis

    BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...

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  • Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to misinterpretation of disease progression. Studies have...

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    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients

    Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...

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  • Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG is to further the promotion of knowledge about the...

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    Angle Closure SIG

    Angle Closure SIG

    SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...

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  • Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee (4), Sung Ryul Shim (5), Ahnul Ha (6) 1 Department...

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    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis

    Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...

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  • Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather Eliassen (3,4,5,6), Lisa Frueh (3), Clary B Clish (7),...

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    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

    Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...

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  • Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês Silva (1), João Barbosa-Breda (1,2,3), Joana Araújo...

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    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists

    Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...

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  • Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which can occur with drugs such as topiramate. The...

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    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure

    The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...

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  • Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma filtration surgery (1). Cataract surgery causes anterior...

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    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery

    The accelerated development of cataract is frequently seen in the years following glaucoma...

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Genetic Epidemiology SIG

SIG Corner

Genetic Epidemiology SIG

SIG Corner Editor: João Barbosa Breda Chair: Ananth Viswanathan Co-chair: Fotis Topouzis NGP Co-chair: Anthony Khawaja NGP Co-chair: Panayiota...

September 30, 2019

Clinical examination of the optic nerve head

Pearl

Clinical examination of the optic nerve head

Pearls Manager: Andrew Tatham Cup/disc ratio (CDR) depends on optic disc size. A large CDR in an eye with a normal large disc may be erroneously...

September 30, 2019

When performing a laser peripheral iridotomy (LPI) for primary angle closure the position of the iridotomy in relation to the eyelid should always be considered

Tip of the month

When performing a laser peripheral iridotomy (LPI) for primary angle closure the position of the iridotomy in relation to the eyelid should always be considered

The Science behind the Tip (1,2,3) The incidence of reported dysphotopsias after an LPI varies from 2% to 11% with linear dysphotopsia and...

July 31, 2019

Avoid the use of monocular prostaglandin analogue medication

Tip of the month

Avoid the use of monocular prostaglandin analogue medication

The Science behind the Tip Where glaucoma predominantly affects one eye, monocular therapy may be used. Prostaglandin analogues are widely used as...

July 31, 2019

Effect of trabeculectomy on corneal endothelial cell loss

Clinical paper of the month

Effect of trabeculectomy on corneal endothelial cell loss

Author(s): Hirooka K (1), Nitta E (2), Ukegawa K (2), Sato S (2), Kiuchi Y (3) 1 Ophthalmology and Visual Science, Hiroshima University, Hiroshima,...

July 31, 2019

Potential role of P2X7 receptor in neurodegenerative processes in a murine model of glaucoma

Experimental Paper of the Month

Potential role of P2X7 receptor in neurodegenerative processes in a murine model of glaucoma

Author(s): Pérez de Lara MJ (1), Avilés-Trigueros M (2), Guzmán-Aránguez A (1), Valiente-Soriano FJ (2), de la Villa P (3), Vidal-Sanz M (4),...

July 31, 2019

Adherence to glaucoma medication

Pearl

Adherence to glaucoma medication

Pearls Manager: Andrew Tatham Obstacles to glaucoma medication adherence include; 1) situational and environmental factors such as major life...

July 30, 2019

Surgery SIG

SIG Corner

Surgery SIG

SIG Corner Editor: João Barbosa Breda Chair: Julián Garcia-Feijoo Co-chair: Keith Barton 1. Ongoing projects SURGERY REGISTRY The European Glaucoma...

July 26, 2019

Prevalence of Treatment With Glaucoma Medication in Scotland, 2010-2017

NGP Paper

Prevalence of Treatment With Glaucoma Medication in Scotland, 2010-2017

Author(s): Alan P Rotchford (1), John Hughes (2), Pankaj Kumar Agarwal (3), Andrew J Tatham (3) Ophthalmology, Tennent Institute of Ophthalmology,...

July 20, 2019

A glaucoma patient who progresses despite presumed good adherence might be using inadequate or insufficient technique when applying the anti-glaucomatous eye drops

Tip of the month

A glaucoma patient who progresses despite presumed good adherence might be using inadequate or insufficient technique when applying the anti-glaucomatous eye drops

The Science behind the Tip It is well known that if poor technique is used when a drop is applied to the eye it does not reach its target. This can...

June 30, 2019

Risk factors for disease progression in low-teens normal-tension glaucoma

Clinical paper of the month

Risk factors for disease progression in low-teens normal-tension glaucoma

Author(s): Baek SU (1,2), Ha A (3,4), Kim DW (5,6), Jeoung JW (3,4), Park KH (3,4), Kim YK (7,4) 1 Department of Ophthalmology, Hallym University...

June 30, 2019

Impact of Posterior Sclera on Glaucoma Progression in Treated Myopic Normal-Tension Glaucoma Using Reconstructed Optical Coherence Tomographic Images

Experimental Paper of the Month

Impact of Posterior Sclera on Glaucoma Progression in Treated Myopic Normal-Tension Glaucoma Using Reconstructed Optical Coherence Tomographic Images

Author(s): Kim YC (1), Koo YH (2), Jung KI (3), Park CK (3) 1 Department of Ophthalmology, College of Medicine, Incheon St. Mary's Hospital, The...

June 30, 2019

Glaucoma due to corticosteroids

Pearl

Glaucoma due to corticosteroids

Pearls Manager: Andrew Tatham Topical, intravitreal or systemic corticosteroids can induce acute or chronic intraocular pressure elevation. Risk...

June 30, 2019

Neuroprotection SIG

SIG Corner

Neuroprotection SIG

SIG Corner Editor: João Barbosa Breda Chair: Francesca Cordeiro Co-chair: Miriam Kolko 1. Goals of the SIG SIG neuroprotection forms the basis of...

June 27, 2019

Selective Laser Trabeculoplasty (SLT) can be considered as the first treatment for newly diagnosed patients with ocular hypertension and mild to moderate primary open angle glaucoma

Tip of the month

Selective Laser Trabeculoplasty (SLT) can be considered as the first treatment for newly diagnosed patients with ocular hypertension and mild to moderate primary open angle glaucoma

The Science behind the Tip The LiGHT trial compared two treatment pathways for treatment naïve ocular hypertension and mild to moderate glaucoma....

May 31, 2019

Exogenous influences on intraocular pressure

Clinical paper of the month

Exogenous influences on intraocular pressure

Author(s): Kim YW (1), Park KH (2) 1 Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea. 2 Ophthalmology, Seoul National...

May 31, 2019

Rapamycin Removes Damaged Mitochondria and Protects Human Trabecular Meshwork (TM-1) Cells from Chronic Oxidative Stress

Experimental Paper of the Month

Rapamycin Removes Damaged Mitochondria and Protects Human Trabecular Meshwork (TM-1) Cells from Chronic Oxidative Stress

Author(s): He JN (1,2), Zhang SD (3), Qu Y (2), Wang HL (2), Tham CC (1), Pang CP (1), Chu WK (4) 1 Department of Ophthalmology and Visual...

May 31, 2019

Angle Closure SIG

SIG Corner

Angle Closure SIG

SIG Corner Editor: João Barbosa Breda Chair: John Thygesen Co-chair: Gus Gazzard 1. Goals and Activities of the SIG The Angle Closure SIG promotes...

May 30, 2019

Glaucoma and intraocular bleeding

Pearl

Glaucoma and intraocular bleeding

Pearls Manager: Andrew Tatham Either acute bleeding in the anterior chamber or long standing blood in the vitreous of any source can cause IOP...

May 30, 2019

Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial

Clinical paper of the month

Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial

Author(s): Gazzard G (1), Konstantakopoulou E (2), Garway-Heath D (2), Garg A (2), Vickerstaff V (3), Hunter R (4), Ambler G (5), Bunce C (6),...

April 30, 2019

Border Tissue Morphology is Spatially Associated with Focal Lamina Cribrosa Defect and Deep-Layer Microvasculature Dropout in Open-Angle Glaucoma

Experimental Paper of the Month

Border Tissue Morphology is Spatially Associated with Focal Lamina Cribrosa Defect and Deep-Layer Microvasculature Dropout in Open-Angle Glaucoma

Author(s): Han JC (1), Choi JH (1), Park DY (1), Lee EJ (1), Kee C (2) 1 Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan...

April 30, 2019

Management of glaucoma during pregnancy

Pearl

Management of glaucoma during pregnancy

Pearls Manager: Andrew Tatham Women with glaucoma of child bearing age should be informed about the possible need to modify treatment during...

April 30, 2019

Imaging SIG

SIG Corner

Imaging SIG

SIG Corner Editor: João Barbosa Breda Chair: Hans LemijCo-chair: David Garway-Heath 1. Goals and Activities of the SIG The Imaging SIG’s main...

April 01, 2019

Ocular coherence tomography (OCT) should be used cautiously in the context of uveitic glaucoma

Tip of the month

Ocular coherence tomography (OCT) should be used cautiously in the context of uveitic glaucoma

The Science behind the Tip Patients with uveitis have a heightened risk of developing secondary glaucoma. Ocular Coherence Tomography (OCT) imaging...

March 31, 2019

Visual Crowding in Glaucoma

Clinical paper of the month

Visual Crowding in Glaucoma

Author(s): Ogata NG (1), Boer ER (2), Daga FB (1), Jammal AA (1), Stringham JM (1), Medeiros FA (1) 1 Duke Eye Center, Department of Ophthalmology,...

March 31, 2019