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Consider a concomitant neurological disease in a glaucoma patient when there is only partial topographic agreement between structure and function.
The Science behind the Tip One of the key elements in the diagnosis and monitoring of glaucoma is...
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Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition
Purpose: Glucocorticoid-induced glaucoma (GIG) is a prevalent complication associated with...
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Peripheral blood mononuclear cell respiratory function is associated with progressive glaucomatous vision loss
Intraocular pressure (IOP) is currently the only modifiable risk factor for glaucoma and all...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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The Collaborative Normal Tension Glaucoma Study (CNTGS)
Pearls Manager: Andrew Tatham The CNTGS compared treatment versus no treatment in patients with normal tension glaucoma who had verified...
July 30, 2020
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Ask your glaucoma patients about mobility rather than vision
The Science behind the Tip Self-reported visual disability in glaucoma which correlates with level of visual field loss includes bumping into...
June 30, 2020
Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial
Author(s): David M.Wright (1,2), Evgenia Konstantakopoulou (3,4,5), Giovanni Montesano (6), Neil Nathwani (3), Anurag Garg (3), David Garway-Heath...
June 30, 2020
Using Deep Learning to Automate Goldmann Applanation Tonometry Readings
Author(s): Ted Spaide (1), Yue Wu (1), Ryan T Yanagihara (1), Shu Feng (1), Omar Ghabra (1), Jonathan S Yi (1), Philip P Chen (1), Francy Moses...
June 30, 2020
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Wound healing is one of the main determinants of long-term intraocular pressure control after filtering surgery
Pearls Manager: Andrew Tatham Risk factors for conjunctival scarring include young age, African ancestry, inflammatory eye disease, long-term...
June 18, 2020
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Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic
The Science behind the Tip The prevalence of ocular surface disease is significantly higher in glaucoma patients (1). While generally accepted that...
May 31, 2020
Franz Fankhauser: the father of the automated perimeter
Author(s): Gloor BP Zürich, Switzerland. Franz Fankhauser is known as the father of automated perimetry and of the q-switched Nd:YAG laser knife....
May 31, 2020
Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System
Author(s): Ikegami K, Shigeyoshi Y, Masubuchi S PURPOSE: Elevated IOP can cause the development of glaucoma. The circadian rhythm of IOP depends on...
May 31, 2020
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Individualized glaucoma treatment
Pearls Manager: Andrew Tatham Individualized glaucoma treatment aims at providing glaucoma management tailored to the individual needs of the...
May 30, 2020
Exfoliation SIG
Chair: Gabor Hollo Co-chair: Anastasios Konstas The goal of this SIG is to increase ophthalmologists’ knowledge on XFS and XFG, and to support the...
May 24, 2020
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Late in-the-bag intraocular lens dislocation several years after uncomplicated cataract surgery is relatively common in pseudoexfoliation
The Science behind the Tip In pseudoexfoliation syndrome (PSX) and pseudoexfoliative glaucoma (PSG) progressive zonular damage frequently leads to...
March 31, 2020
The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study
Author(s): Newman-Casey PA (1), Niziol LM (2), Gillespie BW (3), Janz NK (4), Lichter PR (2), Musch DC (5) 1 Department of Ophthalmology and Visual...
March 31, 2020
Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry
Author(s): Genetics of Glaucoma in People of African Descent (GGLAD) Consortium, Hauser MA (1,2,3,4), Allingham RR (2,3,4), Aung T (3,4,5,6), Van...
March 31, 2020
Care Delivery SIG
SIG Corner Editor: João Barbosa Breda Chair: Anton B. Hommer Co-chair: Gábor Holló The goal of this SIG is to keep an updated overview of glaucoma...
March 31, 2020
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Glaucoma Gel Implant Learning Curve in a Teaching Tertiary Hospital
Author(s):* Raquel Esteves Marques (1,2), Nuno Pinto Ferreira (1,2), David Cordeiro Sousa (1,2,3), Joana Pinto (1,2), André Barata (1,2), Paula...
March 30, 2020
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Glaucoma associated with retinal detachment
Pearls Manager: Andrew Tatham Retinal detachment is usually associated with reduction of intraocular pressure (IOP) but long standing retinal...
March 30, 2020
Aniridia and Axenfeld-Rieger Syndrome: Clinical Presentations, Molecular Genetics and Current/Emerging Therapies
Author(s): Paul W Chrystal (1), Michael A Walter (2) 1 Department of Medical Genetics, University of Alberta, Edmonton, AB, Canada. 2 Department of...
February 29, 2020
Electrophysiology in Glaucoma
Author(s): Senger C (1), Moreto R (1), Watanabe SES ()2, Matos AG (1), Paula JS (1) 1 Department of Ophthalmology, Otorhinolaryngology and Head and...
February 29, 2020
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Consider Brinzolamide to prevent IOP Spikes after Cataract Surgery in Eyes with Glaucoma
The Science behind the Tip IOP spikes, i.e. an IOP elevation after surgery compared to baseline, often occur in eyes with glaucoma.2 IOP spikes may...
February 28, 2020
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Visual Field Progression
Pearls Manager: Andrew Tatham Visual field progression analyses may be event or trend-based. Trend analyses quantify rate of progression, usually...
February 20, 2020
Next Generation Partnership SIG
SIG Corner Editor: João Barbosa Breda Chair: Gauti Jóhannesson Co-chairs: Esther Hoffmann, Francesco Oddone, Anthony Khawaja What is the NGP? The...
February 19, 2020
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When intraocular pressure lowering does not halt visual field progression in an eye which has classic features of glaucoma (glaucoma cupping, retinal nerve fiber loss and normal visual acuity and colour vision), a diagnosis of compressive optic neuropathy should be considered. While disc pallor is recognised to be a sign of potential ominous disease, it should be appreciated that in the early stages of compressive optic neuropathy, the disc may maintain its normal colour
The Science behind the Tip Axonal loss decreases the volume of the disc, and if loss is concentrated in one area without significant gliosis,...
December 31, 2019
Human versus Machine: Comparing a Deep Learning Algorithm to Human Gradings for Detecting Glaucoma on Fundus Photographs
Author(s): Jammal AA (1), Thompson AC (2), Mariottoni EB (2), Berchuck SI (3), Urata CN (2), Estrela T (2), Wakil SM (2), Costa VP (4), Medeiros FA...
December 31, 2019
Impairment of Membrane Repolarization Accompanies Axon Transport Deficits in Glaucoma
Author(s): Fischer RA (1), Risner ML (2,3), Roux AL (2), Wareham LK (2), Sappington RM (1,2,3) 1 Department of Pharmacology, Vanderbilt University,...
December 31, 2019
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Intravenous Hypertonic Saline to Lower Intraocular Pressure in Ocular Hypertension and Primary Open-angle and Exfoliation Glaucoma
Author(s): Pia Katriina Inborr (1), Mika Harju, Tero T Kivelä Department of Ophthalmology, Helsinki University Hospital and University of Helsinki,...
December 30, 2019