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Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization
Purpose: Glaucoma is the primary cause of permanent vision loss worldwide. However, the...
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Quality of Life and Primary Open-Angle Glaucoma in the Ocular Hypertension Treatment Study
Importance: If preperimetric glaucoma reduces patient-reported vision-related quality of life...
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Fatal beauty: which cosmetics are your glaucoma patients using?
Colorism refers to the difference in social treatment between light-skinned and dark-skinned...
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The relationship between multiple deprivation and severity of glaucoma at diagnosis
BACKGROUND: Socioeconomic deprivation is associated with higher odds of chronic diseases, with...
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Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank
Author(s): Oana A Zeleznik ° (1,2), Jae H Kang ° (3,4), Jessica Lasky-Su (3,4), A Heather...
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Be aware of the potential influence of the vitreoretinal interface when interpreting OCT images of the retinal nerve fiber layer (RNFL) in glaucoma patients
Vitreous traction can cause artifacts that may obscure RNFL thinning, potentially leading to...
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Placebo effect and its determinants in ocular hypotensive therapy: meta-analysis and multiple meta-regression analysis
Author(s): Sooyeon Choe (1), Young Kook Kim (2), Woosuk Chung (3), Donghyun Ko (3), Marvin Lee...
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Angle Closure SIG
SIG Corner Editor: Hana Abouzeid Chair: John Thygesen Co-chair: Gus Gazzard The goal of this SIG...
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Comparison of Trabeculectomy Outcomes Performed by Residents in Training and Ophthalmologists
Author(s): Mário Lima-Fontes (1), Ana Faria-Pereira (1), Mariana Leuzinger-Dias (1), Marta Inês...
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Oral acetazolamide (Diamox) is known to lower intraocular pressure, but it can very rarely cause acute bilateral angle closure with severely elevated intraocular pressure
The mechanism is thought to be an idiosyncratic reaction to sulphonamides, similar to that which...
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Cataract Surgery in Patients with Functioning Glaucoma Filtration Surgery
The accelerated development of cataract is frequently seen in the years following glaucoma...
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Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases
Author(s): Bryn L Brazile (1), Bin Yang (1,2), Susannah Waxman (1) , Po Lam (1), Andrew P Voorhees (1), Yi Hua (1), Ralitsa T Loewen (1), Nils A...
October 31, 2020
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Malignant glaucoma
Pearls Manager: Andrew Tatham Malignant glaucoma or aqueous misdirection is a rare type of secondary angle closure glaucoma most commonly...
October 20, 2020
Angle Closure - Relevant breakthroughs in this field
2.1 Should laser peripheral iridotomy (LPI) be performed in primary angle-closure suspect (PACS) patients? Last year we covered the EAGLE and ZAP...
October 01, 2020
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Glaucoma progression: watch out the fellow, non-progressing eye
In clinical practice, the detection of visual field progression in one eye usually leads to management modifications in that eye. Less attention is...
September 30, 2020
Cardiovascular Disease may predict structural and functional progression in early glaucoma
Author(s): Henry Marshall (1), Sean Mullany (2), Ayub Qassim (2), Mark Hassall (2), Owen Siggs (2), Bronwyn Ridge (2), Thi Nguyen (2), Mona...
September 30, 2020
Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study
Author(s): Xiaoran Chai (1,2,3), Kok Yao Low (1,4), Yih Chung Tham (1), Miao Li Chee (1), Sahil Thakur (1), Liang Zhang (1), Nicholas Y Tan (1),...
September 30, 2020
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Mutations in SPATA13/ASEF2 Cause Primary Angle Closure Glaucoma
Author(s): Naushin H Waseem (1), Sancy Low (2,3,4), Amna Z Shah (3), Deepa Avisetti (5), Pia Ostergaard (6), Michael Simpson (7), Katarzyna A...
September 30, 2020
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Optimising eye drop instillation
Pearls Manager: Andrew Tatham When two eye drops are instilled 30 seconds apart, almost 50% of the first drug will be washed out. It is recommended...
September 30, 2020
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Take care not to miss glaucomatous cupping in patients with small discs!
The Science behind the Tip The diagnosis of glaucoma can be missed in patients with small optic discs (1). In such patients, relative crowding of...
July 31, 2020
Longitudinal Macular Structure–Function Relationships in Glaucoma
Author(s): Vahid Mohammadzadeh (1), Alessandro Rabiolo (2), Qiang Fu (3), Esteban Morales (1), Anne L Coleman (1), Simon K Law (1), Joseph Caprioli...
July 31, 2020
Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems
Author(s): Hee Kyung Yang (1), Young Jae Kim (2), Jae Yun Sung (1), Dong Hyun Kim (1), Kwang Gi Kim (3), Jeong-Min Hwang (4) 1 Department of...
July 31, 2020
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The Collaborative Normal Tension Glaucoma Study (CNTGS)
Pearls Manager: Andrew Tatham The CNTGS compared treatment versus no treatment in patients with normal tension glaucoma who had verified...
July 30, 2020
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Ask your glaucoma patients about mobility rather than vision
The Science behind the Tip Self-reported visual disability in glaucoma which correlates with level of visual field loss includes bumping into...
June 30, 2020
Visual Field Outcomes from the Multicenter, Randomized Controlled Laser in Glaucoma and Ocular Hypertension Trial
Author(s): David M.Wright (1,2), Evgenia Konstantakopoulou (3,4,5), Giovanni Montesano (6), Neil Nathwani (3), Anurag Garg (3), David Garway-Heath...
June 30, 2020
Using Deep Learning to Automate Goldmann Applanation Tonometry Readings
Author(s): Ted Spaide (1), Yue Wu (1), Ryan T Yanagihara (1), Shu Feng (1), Omar Ghabra (1), Jonathan S Yi (1), Philip P Chen (1), Francy Moses...
June 30, 2020
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Wound healing is one of the main determinants of long-term intraocular pressure control after filtering surgery
Pearls Manager: Andrew Tatham Risk factors for conjunctival scarring include young age, African ancestry, inflammatory eye disease, long-term...
June 18, 2020
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Glaucoma patients on topical treatment should be routinely checked for signs of ocular surface disease even if they are asymptomatic
The Science behind the Tip The prevalence of ocular surface disease is significantly higher in glaucoma patients (1). While generally accepted that...
May 31, 2020
Franz Fankhauser: the father of the automated perimeter
Author(s): Gloor BP Zürich, Switzerland. Franz Fankhauser is known as the father of automated perimetry and of the q-switched Nd:YAG laser knife....
May 31, 2020
Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System
Author(s): Ikegami K, Shigeyoshi Y, Masubuchi S PURPOSE: Elevated IOP can cause the development of glaucoma. The circadian rhythm of IOP depends on...
May 31, 2020
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Individualized glaucoma treatment
Pearls Manager: Andrew Tatham Individualized glaucoma treatment aims at providing glaucoma management tailored to the individual needs of the...
May 30, 2020
Exfoliation SIG
Chair: Gabor Hollo Co-chair: Anastasios Konstas The goal of this SIG is to increase ophthalmologists’ knowledge on XFS and XFG, and to support the...
May 24, 2020
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Late in-the-bag intraocular lens dislocation several years after uncomplicated cataract surgery is relatively common in pseudoexfoliation
The Science behind the Tip In pseudoexfoliation syndrome (PSX) and pseudoexfoliative glaucoma (PSG) progressive zonular damage frequently leads to...
March 31, 2020
The Association between Medication Adherence and Visual Field Progression in the Collaborative Initial Glaucoma Treatment Study
Author(s): Newman-Casey PA (1), Niziol LM (2), Gillespie BW (3), Janz NK (4), Lichter PR (2), Musch DC (5) 1 Department of Ophthalmology and Visual...
March 31, 2020
Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry
Author(s): Genetics of Glaucoma in People of African Descent (GGLAD) Consortium, Hauser MA (1,2,3,4), Allingham RR (2,3,4), Aung T (3,4,5,6), Van...
March 31, 2020
Care Delivery SIG
SIG Corner Editor: João Barbosa Breda Chair: Anton B. Hommer Co-chair: Gábor Holló The goal of this SIG is to keep an updated overview of glaucoma...
March 31, 2020